Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
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Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interactionTargeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in miceEriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets.Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cellsIdentification of novel inhibitors that disrupt STAT3-DNA interaction from a γ-AApeptide OBOC combinatorial libraryIndividual interferon regulatory factor-3 thiol residues are not critical for its activation following virus infection.Inhibition of STAT3 by Anticancer Drug BendamustineAllosteric Communication across STAT3 Domains Associated with STAT3 Function and Disease-Causing Mutation.Crispene E, a cis-clerodane diterpene inhibits STAT3 dimerization in breast cancer cells.A small molecule compound targeting STAT3 DNA-binding domain inhibits cancer cell proliferation, migration, and invasion.CRM1 is a cellular target of curcumin: new insights for the myriad of biological effects of an ancient spice.Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors.Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia.Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells.
P2860
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P2860
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@ast
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@en
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@nl
type
label
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@ast
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@en
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@nl
prefLabel
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@ast
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@en
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@nl
P2093
P2860
P356
P1433
P1476
Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development
@en
P2093
Andreas Herrmann
Anne Schroeder
David Horne
Fumiko Yakushijin
Gabriel Gugiu
Hongzhi Li
Jianping Lin
John C Williams
P2860
P304
P356
10.1021/CB100253E
P577
2011-02-16T00:00:00Z