Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.

Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.

Item
http://www.wikidata.org/entity/Q34996618
Brain abnormalities in tuberous sclerosis complex.Evidence for population variation in TSC1 and TSC2 gene expressionAnalysis of TSC cortical tubers by deep sequencing of TSC1, TSC2 and KRAS demonstrates that small second-hit mutations in these genes are rare events.Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways.Monoallelic germline TSC1 mutations are permissive for T lymphocyte development and homeostasis in tuberous sclerosis complex individuals.Skin-derived precursor cells as an in vitro modelling tool for the study of type 1 neurofibromatosisTumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.Effects of somatic mutations are associated with SNP in the progression of individual acute myeloid leukemia patient: the two-hit theory explains inherited predisposition to pathogenesis.Leukemogenesis caused by incapacitated GATA-1 function.Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.Inactivation of the p16 gene by hypermethylation and loss of heterozygosity in adenocarcinoma of the lung.
P2860

Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.

Item
http://www.wikidata.org/entity/Q34996618
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@ast
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@en
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@nl
type
label
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@ast
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@en
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@nl
prefLabel
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@ast
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@en
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Pathogenesis of hereditary tumors: beyond the "two-hit" hypothesis.
@en
P2093
P2860
P304
P31
P356
10.1034/J.1399-0004.2002.620501.X
P433
P478
P577
P698