The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
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Molecular mechanisms of biological aging in intervertebral discsAn overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial jointsPhysiological consequences of defects in ERCC1-XPF DNA repair endonucleaseMitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degenerationA Histopathological Scheme for the Quantitative Scoring of Intervertebral Disc Degeneration and the Therapeutic Utility of Adult Mesenchymal Stem Cells for Intervertebral Disc Regeneration.Simulated-physiological loading conditions preserve biological and mechanical properties of caprine lumbar intervertebral discs in ex vivo cultureThe expression of osteoprotegerin is required for maintaining the intervertebral disc endplate of aged mice.Inflammation induces irreversible biophysical changes in isolated nucleus pulposus cells.Spine degeneration in a murine model of chronic human tobacco smokersAn in vitro tissue model to study the effect of age on nucleus pulposus cellsAccelerated aging of intervertebral discs in a mouse model of progeria.Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration.Multi-scale structural and tensile mechanical response of annulus fibrosus to osmotic loadingSerum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases.Genotoxic stress accelerates age-associated degenerative changes in intervertebral discsPharmacological enhancement of disc diffusion and differentiation of healthy, ageing and degenerated discs : Results from in-vivo serial post-contrast MRI studies in 365 human lumbar discsGenetic polymorphisms associated with intervertebral disc degeneration.Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging.MyD88-dependent Toll-like receptor 4 signal pathway in intervertebral disc degeneration.The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) DegenerationLink protein N-terminal peptide binds to bone morphogenetic protein (BMP) type II receptor and drives matrix protein expression in rabbit intervertebral disc cellsThe management of a patient with a cervical disc herniation: a case report.Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells.Photo-crosslinked alginate hydrogels support enhanced matrix accumulation by nucleus pulposus cells in vivo.Investigating the role of DNA damage in tobacco smoking-induced spine degeneration.The effect of extracellular pH on matrix turnover by cells of the bovine nucleus pulposusSoluble factors from the notochordal-rich intervertebral disc inhibit endothelial cell invasion and vessel formation in the presence and absence of pro-inflammatory cytokines.The distribution of fibrillin-2 and LTBP-2, and their co-localisation with fibrillin-1 in adult bovine tail disc.An in vivo model of reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertebral disc.Primary bovine intervertebral disc cells transduced with adenovirus overexpressing 12 BMPs and Sox9 maintain appropriate phenotype.T1ρ magnetic resonance imaging quantification of early lumbar intervertebral disc degeneration in healthy young adults.Reduced nucleus pulposus glycosaminoglycan content alters intervertebral disc dynamic viscoelastic mechanics.The structure and degradation of aggrecan in human intervertebral discEffects of TGF-β1 and IL-1β on expression of ADAMTS enzymes and TIMP-3 in human intervertebral disc degeneration.Effects of Inflammation on Multiscale Biomechanical Properties of Cartilaginous Cells and Tissues.Spatial geometric and magnetic resonance signal intensity changes with advancing stages of nucleus pulposus degeneration.Inflammatory biomarkers of low back pain and disc degeneration: a review.RNA sequencing identifies gene regulatory networks controlling extracellular matrix synthesis in intervertebral disk tissues.Evaluation of Lumbar Intervertebral Disc Degeneration Using T1ρ and T2 Magnetic Resonance Imaging in a Rabbit Disc Injury Model.
P2860
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P2860
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@ast
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@en
type
label
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@ast
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@en
prefLabel
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@ast
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@en
P2093
P356
P1476
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc.
@en
P2093
P304
P356
10.1042/BST0300869
P577
2002-11-01T00:00:00Z