Carfilzomib demonstrates broad anti-tumor activity in pre-clinical non-small cell and small cell lung cancer models.
about
New Insights into the Function of the Immunoproteasome in Immune and Nonimmune CellsThe novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5Carfilzomib combined with suberanilohydroxamic acid (SAHA) synergistically promotes endoplasmic reticulum stress in non-small cell lung cancer cell lines.Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells.Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis.Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells.Emerging role of immunoproteasomes in pathophysiology.Elevated RABEX-5 protein expression predicts poor prognosis in combined small cell lung cancer.Polymer nanoassemblies with solvato- and halo-fluorochromism for drug release monitoring and metastasis imaging.Positioning of proteasome inhibitors in therapy of solid malignancies.Tethered polymer nanoassemblies for sustained carfilzomib release and prolonged suppression of proteasome activity.
P2860
Q26774372-61E4E44B-B745-4BB7-BC3E-61E4817901CFQ28392681-BBF91C52-C3F9-4A00-9675-D614BC6AB193Q36578084-D95B9593-0437-4530-9399-3A9A0E7E647FQ37687457-9817DAB2-0DE3-4A81-A619-D4B2CD868634Q37689041-28FA290F-1558-4BC1-B667-AAABC0FE85F8Q38694197-5D3BB20F-6B72-4182-B539-E7BFFC333A61Q38837519-1CC3AA26-1237-46E6-9B09-EC1113D2274EQ40909548-EB073E9B-2BA2-45F6-BA3B-6CC5E5124A8EQ41854532-C1233F80-05E4-4C83-95BC-78E986BE125BQ47353792-89502E0F-83B9-4A07-9C0E-E5E13BE428A6Q52856824-E5AA133B-F47E-4EE1-BD3A-5F9C8CC55FF3
P2860
Carfilzomib demonstrates broad anti-tumor activity in pre-clinical non-small cell and small cell lung cancer models.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@ast
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@en
type
label
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@ast
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@en
prefLabel
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@ast
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@en
P2093
P2860
P1476
Carfilzomib demonstrates broad ...... small cell lung cancer models.
@en
P2093
Amanda F Baker
Barbara J Sands
Janet L Anderl
Liliana Carbajal
Linda L Garland
Neale T Hanke
P2860
P2888
P356
10.1186/S13046-014-0111-8
P577
2014-12-31T00:00:00Z
P6179
1015832532