Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway - Wikidata - wikimedia - TriplyDB

Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway

Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway

http://www.wikidata.org/entity/Q35006524

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An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9 FGF9 can induce endochondral ossification in cranial mesenchyme.Fibroblast growth factor signaling in skeletal development and disease A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation The INT6 cancer gene and MEK signaling pathways converge during zebrafish development SOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Deletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous Osteoarthritis Regulation of osteoblast, chondrocyte, and osteoclast functions by fibroblast growth factor (FGF)-18 in comparison with FGF-2 and FGF-10 The transcription factor SOX9 regulates cell cycle and differentiation genes in chondrocytic CFK2 cells Msx2 is a repressor of chondrogenic differentiation in migratory cranial neural crest cells The genesis of cartilage size and shape during development and evolution The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Identification of SOX9 interaction sites in the genome of chondrocytes Neuronal regulation of the spatial patterning of neurogenesis Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon.Phenotype profile of a genetic mouse model for Muenke syndrome.SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determination Gene disruption of Spred-2 causes dwarfism.A review of crosstalk between MAPK and Wnt signals and its impact on cartilage regeneration Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes.Microgravity induces pelvic bone loss through osteoclastic activity, osteocytic osteolysis, and osteoblastic cell cycle inhibition by CDKN1a/p21.Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth.Vertebrate skeletogenesis PKCε signalling activates ERK1/2, and regulates aggrecan, ADAMTS5, and miR377 gene expression in human nucleus pulposus cells.Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes Porcine SOX9 Gene Expression Is Influenced by an 18 bp Indel in the 5'-Untranslated Region.ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes Adenoviral Mediated Expression of BMP2 by Bone Marrow Stromal Cells Cultured in 3D Copolymer Scaffolds Enhances Bone Formation Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype Regulation of chondrocyte differentiation by actin-severing protein adseverin FGF signaling in the developing endochondral skeleton.Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development

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Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway

http://www.wikidata.org/entity/Q35006524

description

2000 nî lūn-bûn

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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի փետրվարին հրատարակված գիտական հոդված

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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name

Up-regulation of the chondroge ...... tivated protein kinase pathway

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Up-regulation of the chondroge ...... tivated protein kinase pathway

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Up-regulation of the chondroge ...... tivated protein kinase pathway

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Up-regulation of the chondroge ...... tivated protein kinase pathway

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Up-regulation of the chondroge ...... tivated protein kinase pathway

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Proceedings of the National Academy of Sciences of the United States of America

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Up-regulation of the chondroge ...... tivated protein kinase pathway

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P2093

B de Crombrugghe

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M Kan

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S Murakami

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W L McKeehan

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P2860

Sex reversal by loss of the C-terminal transactivation domain of human SOX9

XCL100, an inducible nuclear MAP kinase phosphatase from Xenopus laevis: its role in MAP kinase inactivation in differentiated cells and its expression during early development

Receptor specificity of the fibroblast growth factor family

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

SOX9 directly regulates the type-II collagen gene

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10.1073/PNAS.97.3.1113

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15539

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