A2A adenosine receptor protects tumors from antitumor T cells.
about
Purinergic signalling and cancerAdenosine receptors and asthma in humansA Metabolic Immune Checkpoint: Adenosine in Tumor MicroenvironmentRelevance of tumor-infiltrating lymphocytes in breast cancerCD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppressionCD73-generated adenosine: orchestrating the tumor-stroma interplay to promote cancer growthWays to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytesPrimer on tumor immunology and cancer immunotherapyImmune modulation of the tumor microenvironment for enhancing cancer immunotherapyEctonucleotidases in tumor cells and tumor-associated immune cells: an overviewThe role and regulation of human Th17 cells in tumor immunityCD73 expression is dynamically regulated in the germinal center and bone marrow plasma cells are diminished in its absenceMolecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairsMyeloid cells in the tumor microenvironment: Role of adenosineCyclic AMP Represents a Crucial Component of Treg Cell-Mediated Immune RegulationThe ever-expanding role of HIF in tumour and stromal biologyA2aR antagonists: Next generation checkpoint blockade for cancer immunotherapyAdenosine A2A receptors intrinsically regulate CD8+ T cells in the tumor microenvironmentIncreased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferaseAdenosine receptors in regulation of dendritic cell differentiation and functionContext-Specific and Immune Cell-Dependent Antitumor Activities of α1-AntitrypsinAdenosine receptors as drug targets--what are the challenges?Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.Cancer immunotherapy comes of ageThe immunosuppressive role of adenosine A2A receptors in ischemia reperfusion injury and islet transplantation.Adenosine A2B receptor blockade slows growth of bladder and breast tumors.Immunological alterations mediated by adenosine during host-microbial interactionsAdenosine receptor A2A deficiency in leukocytes increases arterial neointima formation in apolipoprotein E-deficient miceMuch ado about adenosine: adenosine synthesis and function in regulatory T cell biology.The role of adenosine A2A receptor signaling in bronchiolitis obliterans.A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells.Adenosine arrests breast cancer cell motility by A3 receptor stimulation.Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.Cerebral blood flow response in adenosine 2a receptor knockout mice during transient hypoxic hypoxia.CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppressionAdenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation.Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis.Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment.Blockade of adenosine A2A receptor enhances CD8+ T cells response and decreases regulatory T cells in head and neck squamous cell carcinoma.
P2860
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P2860
A2A adenosine receptor protects tumors from antitumor T cells.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
A2A adenosine receptor protects tumors from antitumor T cells.
@ast
A2A adenosine receptor protects tumors from antitumor T cells.
@en
type
label
A2A adenosine receptor protects tumors from antitumor T cells.
@ast
A2A adenosine receptor protects tumors from antitumor T cells.
@en
prefLabel
A2A adenosine receptor protects tumors from antitumor T cells.
@ast
A2A adenosine receptor protects tumors from antitumor T cells.
@en
P2093
P2860
P356
P1476
A2A adenosine receptor protects tumors from antitumor T cells
@en
P2093
Dmitriy Lukashev
Edwin K Jackson
Elieser Gorelik
Franca Ronchese
Jiang-Fan Chen
Michael K K Wong
Michail Sitkovsky
Patrick Smith
Scott Abrams
P2860
P304
13132-13137
P356
10.1073/PNAS.0605251103
P407
P50
P577
2006-08-17T00:00:00Z