Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering.
about
Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experienceTargeted DNA mutagenesis for the cure of chronic viral infectionsProgress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseasesNon-specific protein-DNA interactions control I-CreI target binding and cleavageMining endonuclease cleavage determinants in genomic sequence data.Improved modeling of side-chain--base interactions and plasticity in protein--DNA interface designThe developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vectorZinc-finger nucleases for somatic gene therapy: the next frontier.Efficient design of meganucleases using a machine learning approach.Computational library design for increasing haloalkane dehalogenase stability.Homing endonucleases: from genetic anomalies to programmable genomic clippersComprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications.EENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineeringPerpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preferenceReprogramming homing endonuclease specificity through computational design and directed evolution.Molecular scissors for in situ cellular repair.Recent advances in targeted genome engineering in mammalian systems.Computational enzyme design.Computational design gains momentum in enzyme catalysis engineering.Statistical analysis of structural determinants for protein-DNA-binding specificity.A computational strategy for altering an enzyme in its cofactor preference to NAD(H) and/or NADP(H).
P2860
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P2860
Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering.
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Comprehensive computational de ...... ficity for genome engineering.
@ast
Comprehensive computational de ...... ficity for genome engineering.
@en
type
label
Comprehensive computational de ...... ficity for genome engineering.
@ast
Comprehensive computational de ...... ficity for genome engineering.
@en
prefLabel
Comprehensive computational de ...... ficity for genome engineering.
@ast
Comprehensive computational de ...... ficity for genome engineering.
@en
P2860
P356
P1476
Comprehensive computational de ...... ficity for genome engineering.
@en
P2093
Raymond J Monnat
P2860
P304
P356
10.1093/NAR/GKR022
P407
P577
2011-02-01T00:00:00Z