PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation - Wikidata - wikimedia - TriplyDB

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

http://www.wikidata.org/entity/Q35018220

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Novel mechanisms of endothelial mechanotransduction Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF.MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.The arterial microenvironment: the where and why of atherosclerosis.The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cells Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces.Disturbed flow: p53 SUMOylation in the turnover of endothelial cells Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function.BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension ERK5 activation in macrophages promotes efferocytosis and inhibits atherosclerosis.Laminar flow activation of ERK5 leads to cytoprotective effect via CHIP-mediated p53 ubiquitination in endothelial cells Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2 Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction.p53 SUMOylation promotes its nuclear export by facilitating its release from the nuclear export receptor CRM1 PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system.Molecular biology of atherosclerosis.Shear stress and atherosclerosis Role of biomechanical forces in the natural history of coronary atherosclerosis.Effects of shear stress on endothelial cells: go with the flow.Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events.Flow signaling and atherosclerosis.Sub-cellular localization specific SUMOylation in the heart.Biomechanical factors in atherosclerosis: mechanisms and clinical implications.Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases.Zebrafish Model for Functional Screening of Flow-Responsive Genes.Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ßI and prooxidant enzyme NADPH oxidase.Atheroprotective laminar flow inhibits Hippo pathway effector YAP in endothelial cells.Disturbed flow mediated modulation of shear forces on endothelial plane: A proposed model for studying endothelium around atherosclerotic plaques Multiple Functions of Protein Inhibitor of Activated STAT1 in Regulating Endothelial Cell Proliferation and Inflammation.Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion.Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects.

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PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

http://www.wikidata.org/entity/Q35018220

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@ast

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@en

type

label

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@ast

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@en

prefLabel

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@ast

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@en

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Journal of Cell Biology

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PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

@en

P2093

Carolyn McClain

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Chang-Hoon Woo

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Eugene Chang

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Hakjoo Lee

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Jun-ichi Abe

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Keigi Fujiwara

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Michael R King

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Nhat-Tu Le

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Tamlyn Thomas

http://www.w3.org/2001/XMLSchema#string

P2860

p53 has a direct apoptogenic role at the mitochondria

Regulation of human p53 activity and cell localization by alternative splicing

SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

WAF1, a potential mediator of p53 tumor suppression

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

Src kinase regulation by phosphorylation and dephosphorylation

The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis

Oncogenic forms of p53 inhibit p53-regulated gene expression

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

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867-884

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10.1083/JCB.201010051

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5

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193

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Cynthia A Reinhart-King

Bradford C. Berk

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2011-05-01T00:00:00Z

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51177035

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21624955

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3105539

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