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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

http://www.wikidata.org/entity/Q35026110

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Leukemia and benzene Structural Perturbations Induced by the α-Anomer of the Aflatoxin B 1 Formamidopyrimidine Adduct in Duplex and Single-Strand DNA Bypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1 Kinetics of hydrolysis and reaction of aflatoxin B1 exo-8,9-epoxide and relevance to toxicity and detoxication.Mycotoxin Biotransformation by Native and Commercial Enzymes: Present and Future Perspectives Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct Acidic domains around nucleic acids.Photophysics and photochemistry of aflatoxins B1 and B2.Error-prone replication bypass of the primary aflatoxin B1 DNA adduct, AFB1-N7-Gua The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.The surface-enhanced Raman spectra of aflatoxins: spectral analysis, density functional theory calculation, detection and differentiation.A viral genome containing an unstable aflatoxin B1-N7-guanine DNA adduct situated at a unique site The role of aflatoxins in hepatocellular carcinoma.Site-specific targeting of aflatoxin adduction directed by triple helix formation in the major groove of oligodeoxyribonucleotides.Mutational properties of the primary aflatoxin B1-DNA adduct.Prenatal exposure of mice to the human liver carcinogen aflatoxin B1 reveals a critical window of susceptibility to genetic change.Significance of DNA adduct studies in animal models for cancer molecular dosimetry and risk assessment.Quantitative predictability of carcinogenicity of the covalent binding index of chemicals to DNA: comparison of the in vivo and in vitro assays.Detection of 8,9-dihydro-(7'-guanyl)-9-hydroxyaflatoxin B1 in human urine.Genetic differences in susceptibility to chemically induced myelotoxicity and leukemia Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.DNA Sequence Modulates Geometrical Isomerism of the trans-8,9- Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)- 9-hydroxy Aflatoxin B1 Adduct Inherent stereospecificity in the reaction of aflatoxin B(1) 8,9-epoxide with deoxyguanosine and efficiency of DNA catalysis Depurination causes mutations in SOS-induced cells.Monoclonal antibody to aflatoxin B1-modified DNA detected by enzyme immunoassay Chemical and structural characterization of interstrand cross-links formed between abasic sites and adenine residues in duplex DNA.Modification of DNA by aflatoxin B1 creates alkali-labile lesions in DNA at positions of guanine and adenine.Sequential biochemical and histological changes in rats treated with aflatoxin B1.Induction of base substitution mutations by aflatoxin B1 is mucAB dependent in Escherichia coli Creation of a test plasmid for detecting G-C-to-T-A transversions by changing serine to arginine in the active site of beta-lactamase.Quantitation of aflatoxin B1 adduction within the ribosomal RNA gene sequences of rat liver DNA.Present and future directions of translational research on aflatoxin and hepatocellular carcinoma. A review.NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles.In vitro reactions of aflatoxin B1-adducted DNA.DNA repair and mutagenesis in mammalian cells.Aflatoxin B1 dihydrodiol antibody: production and specificity.Reactivity of aflatoxin B2a antibody with aflatoxin B1-modified DNA and related metabolites.

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P2860

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

http://www.wikidata.org/entity/Q35026110

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1977 nî lūn-bûn

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1977 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1977 թվականի մայիսին հրատարակված գիտական հոդված

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1977年の論文

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1977年学术文章

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1977年學術文章

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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Proceedings of the National Academy of Sciences of the United States of America

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Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

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A M Nadzan

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G Büchi

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G N Wogan

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J M Essigmann

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R G Croy

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V N Reinhold

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W F Busby

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P2860

The total synthesis of racemic aflatoxin B1

N-substitution of carbon 8 in guanosine and deoxyguanosine by the carcinogen N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro

Structures of hepatic nucleic acid-bound dyes in rats given the carcinogen N-methyl-4-aminoazobenzene

Alkylation by propylene oxide of deoxyribonucleic acid, adenine, guanosine and deoxyguanylic acid

Structure of 7,12-dimethylbenz(a)anthracene-guanosine adducts.

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

Aflatoxin B1-2,3-oxide as a probable intermediate in the covalent binding of aflatoxins B1 and B2 to rat liver DNA and ribosomal RNA in vivo.

In vitro metabolic conversion of aflatoxins and benzo(alpha)pyrene to nucleic acid-binding metabolites.

Letter: Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adduct.

Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro.

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