Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
about
An overview of targeted alpha therapy.Impact of α-targeted radiation therapy on gene expression in a pre-clinical model for disseminated peritoneal disease when combined with paclitaxel.Radioimmunotherapy with α-particle-emitting radionuclides.Comparison between internalizing anti-HER2 mAbs and non-internalizing anti-CEA mAbs in alpha-radioimmunotherapy of small volume peritoneal carcinomatosis using 212Pb.(212)Pb-radioimmunotherapy induces G(2) cell-cycle arrest and delays DNA damage repair in tumor xenografts in a model for disseminated intraperitoneal disease.Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model.(111)In- and (203)Pb-Labeled Cyclic RGD Peptide Conjugate as an α(v)β(3) Integrin-Binding RadiotracerProduction of [(211)At]-astatinated radiopharmaceuticals and applications in targeted α-particle therapyMolecular pathways: targeted α-particle radiation therapy.Sensitization of tumor to ²¹²Pb radioimmunotherapy by gemcitabine involves initial abrogation of G2 arrest and blocked DNA damage repair by interference with Rad51.Methodology for labeling proteins and peptides with lead-212 (212Pb)212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint.Mechanisms of Cell Killing Response from Low Linear Energy Transfer (LET) Radiation Originating from (177)Lu Radioimmunotherapy Targeting Disseminated Intraperitoneal Tumor XenograftsGene expression profiling upon (212) Pb-TCMC-trastuzumab treatment in the LS-174T i.p. xenograft model.Tumour targeting with radiometals for diagnosis and therapy.General overview of radioimmunotherapy of solid tumors.Matching chelators to radiometals for radiopharmaceuticals.A nuclear chocolate box: the periodic table of nuclear medicine.Relevance of radiobiological concepts in radionuclide therapy of cancer.Search of ligands suitable for (212)Pb/(212)Bi in vivo generators.Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases.Chemical aspects of metal ion chelation in the synthesis and application antibody-based radiotracers.Radioimmunotherapy for delivery of cytotoxic radioisotopes: current status and challenges.
P2860
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P2860
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
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2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@ast
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@en
type
label
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@ast
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@en
prefLabel
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@ast
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@en
P2860
P356
P1433
P1476
Towards translation of 212Pb as a clinical therapeutic; getting the lead in!
@en
P2093
Martin W Brechbiel
P2860
P304
P356
10.1039/C0DT01387K
P407
P577
2011-03-04T00:00:00Z