High-resolution genetic and physical map of the Lgn1 interval in C57BL/6J implicates Naip2 or Naip5 in Legionella pneumophila pathogenesis.
about
Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophilaRepeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolutionCaspase Exploitation by Legionella pneumophilaInnate immune recognition of bacterial ligands by NAIPs determines inflammasome specificityNalp1b controls mouse macrophage susceptibility to anthrax lethal toxinMolecular pathogenesis of infections caused by Legionella pneumophilaThe NOD: a signaling module that regulates apoptosis and host defense against pathogens.Nucleotide-binding oligomerization domain containing-like receptor family, caspase recruitment domain (CARD) containing 4 (NLRC4) regulates intrapulmonary replication of aerosolized Legionella pneumophila.Genomic sequence analysis of the mouse Naip gene array.Mice, microbes and models of infection.Epithelial NAIPs protect against colonic tumorigenesis.Single gene effects in mouse models of host: pathogen interactions.Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.Activation of host mitogen-activated protein kinases by secreted Legionella pneumophila effectors that inhibit host protein translation.Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus.Lgals6, a 2-million-year-old gene in mice: a case of positive Darwinian selection and presence/absence polymorphism.NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.NLR proteins: integral members of innate immunity and mediators of inflammatory diseases.Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.Macrophages from mice with the restrictive Lgn1 allele exhibit multifactorial resistance to Legionella pneumophilaThe inflammasome in host defense.The role of IL-1β in Pseudomonas aeruginosa in lung infection.Comparative Analysis of the Flax Immune Receptors L6 and L7 Suggests an Equilibrium-Based Switch Activation Model.Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila.A hemidominant Naip5 allele in mouse strain MOLF/Ei-derived macrophages restricts Legionella pneumophila intracellular growth.Deviant Behavior: Tick-Borne Pathogens and Inflammasome Signaling.Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila.Strain-dependent neurodevelopmental abnormalities in caspase-3-deficient mice.
P2860
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P2860
High-resolution genetic and physical map of the Lgn1 interval in C57BL/6J implicates Naip2 or Naip5 in Legionella pneumophila pathogenesis.
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@ast
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@en
type
label
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@ast
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@en
prefLabel
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@ast
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@en
P2860
P356
P1433
P1476
High-resolution genetic and ph ...... ella pneumophila pathogenesis.
@en
P2093
J D Growney
W F Dietrich
P2860
P304
P356
10.1101/GR.10.8.1158
P577
2000-08-01T00:00:00Z