Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions - Wikidata - wikimedia - TriplyDB

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

http://www.wikidata.org/entity/Q35030924

about

Glycan Engineering for Cell and Developmental Biology Glycosylated Notch and Cancer Notch-Mediated Cell Adhesion From fly wings to targeted cancer therapies: a centennial for notch signaling Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2 Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function.Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.Analysis of POFUT1 gene mutation in a Chinese family with Dowling-Degos disease Inhibition of fucosylation reshapes inflammatory macrophages and suppresses type II collagen-induced arthritis.Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors The biology of hyperpigmentation syndromes.Aberrant fucosylation of glycosphingolipids in human hepatocellular carcinoma tissues.NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow.Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development Mutations in POFUT1, encoding protein O-fucosyltransferase 1, cause generalized Dowling-Degos disease Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia NOTCH signaling in Sertoli cells regulates gonocyte fate Vertebrate protein glycosylation: diversity, synthesis and function.Notch signaling: switching an oncogene to a tumor suppressor.Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans.Human deficiencies of fucosylation and sialylation affecting selectin ligands.Solving glycosylation disorders: fundamental approaches reveal complicated pathways.The challenge of targeting notch in hematologic malignancies.The multiple roles of epidermal growth factor repeat O-glycans in animal development.Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers.Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands Notch Signaling and Alloreactivity.Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner Biological functions of fucose in mammals.Notch Signaling in the Regulation of Hematopoietic Stem Cell.Novel roles for O-linked glycans in protein folding.Notch2 blockade enhances hematopoietic stem cell mobilization and homing.Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention.Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans.Pre-NOTCH Expression and Processing Pre-NOTCH Processing in the Endoplasmic Reticulum

P2860

Q26765063-B463A6FF-6C3D-46FE-B39E-7FC24245A78C Q26765743-309C769E-E863-4FAD-8D3E-5FEC7B336451 Q26771105-502D3995-FF01-40CC-85E3-DF52A52E3E4B Q27004534-D997E713-39F7-4399-92EC-DB2CFF13DCBE Q27683660-55682393-FE9E-43F4-B17A-DF992954F06A Q28539733-3A49ED82-AD03-4FDA-B8B8-13454B17166B Q28550463-53160A9E-813F-44D5-BC15-4F973E0073FC Q33429438-51787F88-DF80-43B9-A163-418B186004B4 Q33604452-75BAE0CA-99B6-4FEE-BB06-16B417EC1EE2 Q34089476-CD638F99-0CCF-4C5D-8880-CB2507C0577A Q34098241-4AFB6766-FD99-4787-9E0D-F06039338B5F Q34216999-9D0320A7-C7A5-4256-B961-1BBBB4D5D8F5 Q34409196-86359039-6F69-4F72-B982-0F888F82669D Q34884062-C95CEA9C-056D-4E00-B1B9-0AB716AA2AFE Q35408681-F1AC8C48-324B-4AF8-A597-BFC873214DDF Q35568443-72DE6C59-4413-449C-9D84-5B2AF7165E42 Q36136455-2D4B3226-153B-450F-9E80-28CC857886AE Q36389083-21350153-894F-4942-A023-386E33F6C690 Q36909265-AF83A72F-37A9-49B7-8EF2-4A0C541C85A2 Q36973664-F97A0940-2AD5-4EF6-8310-AB6572724152 Q37396888-638D7D1D-E2A6-403D-89D8-EECEE349C1EE Q37601831-15CF7F4A-5E6D-4536-BC4E-EB62F1BE0440 Q37709333-4E139E90-9DEB-4EA9-A871-90832BAFF7D0 Q37993403-2FE00614-F120-47DA-B613-1320BE89196F Q37998408-81B9A854-8E0E-4CA6-9E5E-9074AA545A26 Q38186249-313957CA-21A7-48F4-A378-5971F818BBF3 Q38222770-3339AF7F-FB21-4A75-B759-F6087A1B80AD Q38547337-840986FA-DF70-43B8-95D9-94C3B51F3D46 Q38563527-0B068416-6B1B-4583-944A-BBD9FA08D1DF Q38749981-E33F06AD-F5D1-452F-9E25-197DFDA9AA02 Q38949407-DD255D9C-030A-4704-931A-98F3543BA1E1 Q38977936-8B538BDF-F632-4AB8-B5B6-0EA670B4361F Q39254939-26C3CA7C-2D81-4D4A-A254-C4D930A3F011 Q41310625-C69A465A-B119-4BAC-9345-23DB929D0945 Q42254297-2D66ABFF-821B-4425-8F1A-D25FE734C4DF Q42368326-530246B2-13C5-446A-B56C-025DAF0F3D68 Q42410358-B682EA45-2415-4CC8-A00B-448933E6F2EF Q42987220-8BF4B7F6-0F30-45EB-A2BE-6C65C6F8A9B0 Q45318222-D37EA8AF-8FF4-4A7C-9B9B-794BD84F5566 Q45318225-B5056FD0-9310-4A31-8D96-BF1AC209BE9F

P2860

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

http://www.wikidata.org/entity/Q35030924

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@ast

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@en

type

label

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@ast

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@en

prefLabel

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@ast

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@en

P1433

Q35030924-EC8733F2-0BBB-45BC-B655-36B15BDC7A19

P1476

Q35030924-42F94859-13BE-4CB8-B24E-4E30791B96DA

P2093

Q35030924-37F7FB46-EF1F-4697-9583-7D1BD166B558

Q35030924-568DE8A7-567C-44CA-B20E-0C409581051A

Q35030924-60757D34-33E1-45F7-99B0-D270C7F5D4A7

Q35030924-6E1D723C-DCA1-4BC7-8D85-F0537D99AD86

Q35030924-6F23E38D-3CE4-4B60-AC5E-8C39A6E41D77

Q35030924-713D5DC4-8948-4EF6-8FFA-6EA0D0A61A62

Q35030924-80E59342-16D3-4EF8-A639-1823B7D3FEEE

Q35030924-87CCDCD2-65DB-42F6-8BA3-EFC6A9617FE7

Q35030924-A4CF4463-8E58-453A-B07A-37201189AA00

Q35030924-CB8E2C2D-9BD7-4415-A3B5-8AF3CE91E10F

P2860

Q35030924-02494B42-D920-44D9-BC99-46740AB5F763

Q35030924-037FC4D2-972C-4F9B-AEAA-6A3A1B58CA3E

Q35030924-0EAC0D34-481E-434D-B338-043BD31350CB

Q35030924-1207EB47-647A-4C6B-A0B8-EB5B4F2F16E7

Q35030924-16DE7452-F40C-41D4-8BE4-9142A019DE0D

Q35030924-25E2CEB0-9C52-4DFA-AC90-732D0051221B

Q35030924-290405EA-074A-412A-93B6-4E4BB5F17C6C

Q35030924-29F62E41-C856-459A-B2C5-8180C0796693

Q35030924-379A5A09-7C1A-40CF-B1BF-17CC9BD1E52C

Q35030924-3AE0AF16-FFB1-454A-B1ED-5AA2177132A1

P304

Q35030924-FDA3CB8A-D11F-4B2C-9349-1C5339055B69

P31

Q35030924-085E96FA-B5EE-4519-B5E6-1734227B91C3

P356

Q35030924-2CC44CF6-17E2-4E98-B1FB-E8A40B6D5E3D

P407

Q35030924-714110B5-BD56-40FF-9340-A3436E6F7C27

P433

Q35030924-C6BF9C72-AFB7-419A-A1B8-4AD1C9433348

P478

Q35030924-D3767348-EAC8-40D0-A615-3413FE196D99

P577

Q35030924-14AA38E4-12BD-47F7-BBE5-264C909E8E4A

P5875

Q35030924-9635E835-C6C1-43A1-B40A-03AE756BE306

P698

Q35030924-8095FCC5-994B-46F7-8CDB-CE715538BA02

P932

Q35030924-4E8B7F3F-D924-4B44-A65F-34060B63779A

P356

BLOOD-2010-12-326074

P1433

P1476

Protein O-fucosyltransferase 1 ...... h receptor ligand interactions

@en

P2093

David Yao

http://www.w3.org/2001/XMLSchema#string

John B Lowe

http://www.w3.org/2001/XMLSchema#string

Lan Zhou

http://www.w3.org/2001/XMLSchema#string

Lebing Wei

http://www.w3.org/2001/XMLSchema#string

Pamela Stanley

http://www.w3.org/2001/XMLSchema#string

Quanjian Yan

http://www.w3.org/2001/XMLSchema#string

Stanton Gerson

http://www.w3.org/2001/XMLSchema#string

Wei Xin

http://www.w3.org/2001/XMLSchema#string

Weihuan Wang

http://www.w3.org/2001/XMLSchema#string

Xiaoran Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase

O-fucosylation of notch occurs in the endoplasmic reticulum

Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways

Fringe is a glycosyltransferase that modifies Notch

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe

Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches

The canonical Notch signaling pathway: unfolding the activation mechanism.

Inducible gene targeting in mice

Osteoblastic cells regulate the haematopoietic stem cell niche

P304

5652-5662

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1182/BLOOD-2010-12-326074

http://www.w3.org/2001/XMLSchema#string

P407

P433

21

http://www.w3.org/2001/XMLSchema#string

P478

117

http://www.w3.org/2001/XMLSchema#string

P577

2011-04-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

50999629

http://www.w3.org/2001/XMLSchema#string

P698

21464368

http://www.w3.org/2001/XMLSchema#string

P932

3110024

http://www.w3.org/2001/XMLSchema#string