Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions
about
Glycan Engineering for Cell and Developmental BiologyGlycosylated Notch and CancerNotch-Mediated Cell AdhesionFrom fly wings to targeted cancer therapies: a centennial for notch signalingFringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligandsO-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand functionProtein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function.Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.Analysis of POFUT1 gene mutation in a Chinese family with Dowling-Degos diseaseInhibition of fucosylation reshapes inflammatory macrophages and suppresses type II collagen-induced arthritis.Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptorsThe biology of hyperpigmentation syndromes.Aberrant fucosylation of glycosphingolipids in human hepatocellular carcinoma tissues.NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activationSpecific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow.Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.Lunatic, Manic, and Radical Fringe Each Promote T and B Cell DevelopmentMutations in POFUT1, encoding protein O-fucosyltransferase 1, cause generalized Dowling-Degos diseaseTherapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemiaNOTCH signaling in Sertoli cells regulates gonocyte fateVertebrate protein glycosylation: diversity, synthesis and function.Notch signaling: switching an oncogene to a tumor suppressor.Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans.Human deficiencies of fucosylation and sialylation affecting selectin ligands.Solving glycosylation disorders: fundamental approaches reveal complicated pathways.The challenge of targeting notch in hematologic malignancies.The multiple roles of epidermal growth factor repeat O-glycans in animal development.Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers.Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligandsNotch Signaling and Alloreactivity.Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent mannerBiological functions of fucose in mammals.Notch Signaling in the Regulation of Hematopoietic Stem Cell.Novel roles for O-linked glycans in protein folding.Notch2 blockade enhances hematopoietic stem cell mobilization and homing.Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention.Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans.Pre-NOTCH Expression and ProcessingPre-NOTCH Processing in the Endoplasmic Reticulum
P2860
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P2860
Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@ast
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@en
type
label
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@ast
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@en
prefLabel
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@ast
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@en
P2093
P2860
P1433
P1476
Protein O-fucosyltransferase 1 ...... h receptor ligand interactions
@en
P2093
John B Lowe
Lebing Wei
Pamela Stanley
Quanjian Yan
Stanton Gerson
Weihuan Wang
Xiaoran Huang
P2860
P304
P356
10.1182/BLOOD-2010-12-326074
P407
P577
2011-04-04T00:00:00Z