Detecting somatic genetic alterations in tumor specimens by exon capture and massively parallel sequencing.
about
Clinical tumor sequencing: opportunities and challenges for precision cancer medicineESR1 ligand-binding domain mutations in hormone-resistant breast cancer.Recurrent SMARCA4 mutations in small cell carcinoma of the ovary.Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations.Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials.Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data.Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemiaCerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesionsAdvancing clinical oncology through genome biology and technology.GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.Dichotomy of Genetic Abnormalities in PEComas With Therapeutic ImplicationsIntegration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies.Metastatic Competence Can Emerge with Selection of Preexisting Oncogenic Alleles without a Need of New MutationsNF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases.Genomic Characterization of Upper Tract Urothelial CarcinomaTargeted exome sequencing profiles genetic alterations in leiomyosarcoma.Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphologyComprehensive mutation profiling by next-generation sequencing of effusion fluids from patients with high-grade serous ovarian carcinoma.Mammary analog secretory carcinoma of the thyroid gland: A primary thyroid adenocarcinoma harboring ETV6-NTRK3 fusion.NF1 Mutations Are Common in Desmoplastic Melanoma.Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets.Institutional implementation of clinical tumor profiling on an unselected cancer population.Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry.Interest and Attitudes of Patients With Advanced Cancer With Regard to Secondary Germline Findings From Tumor Genomic Profiling.A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers.Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer.PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.Next-generation sequencing of urine specimens: A novel platform for genomic analysis in patients with non-muscle-invasive urothelial carcinoma treated with bacille Calmette-Guérin.A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancerThe oncocytic subtype is genetically distinct from other pancreatic intraductal papillary mucinous neoplasm subtypes.EBV-associated lymphoepithelioma-like carcinoma of the pancreas: Case report with targeted sequencing analysis.Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinomaA phase II study of temsirolimus added to low-dose weekly carboplatin and paclitaxel for patients with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC).Genomic characterization of response to chemoradiation in urothelial bladder cancer.Activating mutation of PDGFRB gene in a rare cardiac undifferentiated intimal sarcoma of the left atrium: a case report.
P2860
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P2860
Detecting somatic genetic alterations in tumor specimens by exon capture and massively parallel sequencing.
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Detecting somatic genetic alte ...... massively parallel sequencing.
@ast
Detecting somatic genetic alte ...... massively parallel sequencing.
@en
type
label
Detecting somatic genetic alte ...... massively parallel sequencing.
@ast
Detecting somatic genetic alte ...... massively parallel sequencing.
@en
prefLabel
Detecting somatic genetic alte ...... massively parallel sequencing.
@ast
Detecting somatic genetic alte ...... massively parallel sequencing.
@en
P2093
P2860
P356
P1476
Detecting somatic genetic alte ...... massively parallel sequencing
@en
P2093
A Rose Brannon
Helen H Won
Michael F Berger
Sasinya N Scott
P2860
P304
P356
10.3791/50710
P577
2013-10-18T00:00:00Z