The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. - Wikidata - wikimedia - TriplyDB

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.

http://www.wikidata.org/entity/Q35033140

about

Sex determination in the Squalius alburnoides complex: an initial characterization of sex cascade elements in the context of a hybrid polyploid genome Molecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fish The many facets of the Wilms' tumour gene, WT1 Asynchronous expression of the homeodomain protein CUX1 in Sertoli cells and spermatids during spermatogenesis in mice.The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in mice Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation.Functional redundancy of TGF-beta family type I receptors and receptor-Smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse.WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland Wt1 negatively regulates beta-catenin signaling during testis development The Sertoli cell: one hundred fifty years of beauty and plasticity.Transcription and post-transcriptional regulation of spermatogenesis.Determination and stability of gonadal sex Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation.Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche Expression of inhibin-alpha is regulated synergistically by Wilms' tumor gene 1 (Wt1) and steroidogenic factor-1 (Sf1) in sertoli cells.Up-regulation of SOX9 in sertoli cells from testiculopathic patients accounts for increasing anti-mullerian hormone expression via impaired androgen receptor signaling The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome.Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene.Altered lipid homeostasis in Sertoli cells stressed by mild hyperthermia.Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation Prmt5 is required for germ cell survival during spermatogenesis in mice.Wilms' tumor protein Wt1 is an activator of the anti-Müllerian hormone receptor gene Amhr2.Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice.Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis.Insulin-Like Growth Factor 1 Receptor-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury.Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.Monitoring therapy with MEK inhibitor U0126 in a novel Wilms tumor model in Wt1 knockout Igf2 transgenic mice using 18F-FDG PET with dual-contrast enhanced CT and MRI: early metabolic response without inhibition of tumor growth.Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids.The molecular and cellular basis of gonadal sex reversal in mice and humans.Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation.Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis.Overactive beta-catenin signaling causes testicular sertoli cell tumor development in the mouse

P2860

Q21143753-D082BD20-BD1D-43EA-90F9-CAB80DCD84C8 Q26849657-EB3D45C2-045E-4AB6-9CFB-5D572890D752 Q28264516-AED5B05B-F739-4FC9-A47E-B3647904656F Q30428024-C350FD17-2B71-467A-967D-DA446A15C59C Q33346730-2262B264-D305-4E4C-AD06-DF1084EFBFC0 Q33503210-8134EA81-BE7E-4F08-A03E-DC94557358DA Q33570650-2C0E2EED-BB1D-464F-BEC3-DF55248572AC Q33585208-42CFC16E-9B2B-4093-9C9C-E04D545A9E0A Q33621021-30F42295-EF4B-4C47-A512-DA1E95A6288D Q33657296-AC453905-8E1D-4A8C-A9E0-4BD6C0C311D2 Q33684753-EC975E87-BDD8-48DF-AAC3-571D98A7BE46 Q33772289-3CC64386-BD44-4A6B-BD44-78B63861C64C Q33856955-6812D4C6-273C-497A-BB25-8EBCCB2F1726 Q33899665-77742234-95E6-40D9-9928-C198FE86A5DB Q34248627-08FE39F0-C1DA-4E07-B37D-7A07331F1083 Q34428960-0EF36CA4-A549-4B47-BE23-6C67ADB81442 Q34539857-F3F9C049-B5EE-4A41-AAAC-7D9BB719E80B Q34541352-A756A363-8108-439A-8619-9B331434E477 Q34551202-06971B9F-93EE-44CE-A4A0-9F8E27BBC4F5 Q34656528-62D54D07-2162-498B-A576-01C3564B04C4 Q34917167-93E110C2-3557-4247-BB08-22114F0584E0 Q34999143-EE07B2ED-F757-4BB4-8488-B423484EDCCA Q35095712-9392D59B-2E73-4BAF-950C-335AF4FC75E4 Q35137408-9177E235-0B50-4743-8431-8AFA8701E19B Q35279994-22EAE524-6212-4DF5-BFB6-7904FF32A08C Q35739889-4E587DF6-D40E-4559-8AA9-3D44B1020678 Q35857103-C90ACCE4-D400-4C7C-95AE-0E4E17E798C0 Q35942294-F0C24264-2A5F-4D18-84B9-FB518D16DB7F Q36002556-70EDECC8-2FB7-41C7-9FC7-470E7CFA5BEF Q36133983-D3DEBFB7-BB31-4731-8F25-2791C84B068F Q36179651-7C8D6F4B-07F2-4C47-BA72-648F7A831176 Q36236310-1EB43CDB-DD65-4C2C-9B5E-ACE2AB378ECA Q36665931-1468F8AD-BB50-4252-8A8E-0B31974770BB Q36862651-B76B1099-BE47-4ACC-9884-693D4C4803A7 Q37005019-25C0F28C-08DC-43B0-AF0E-731617ACAB29 Q37095297-68D6C2EE-4964-44B5-BE69-1E143A969DBF Q37217819-83ABB361-15C8-4C3C-81FA-75819D336971 Q37218003-899282D3-D361-46F1-A932-852D8D69B857 Q37284507-C5973C70-31F6-4BB2-BE43-BF3D21AA9A1F Q37404723-698018C4-AB76-4D9F-9E91-5392520E3D8A

P2860

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.

http://www.wikidata.org/entity/Q35033140

description

2006 nî lūn-bûn

@nan

2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@ast

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@en

type

label

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@ast

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@en

prefLabel

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@ast

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@en

P1433

Q35033140-72701C30-6C52-4B57-88A0-C67653C888A6

P1476

Q35033140-81335298-023C-4398-AED1-BC6D7A7DE688

P2093

Q35033140-0362B8E8-1B32-46C8-838B-304678043844

Q35033140-0E4F8A89-4ECC-464E-86DA-C10FE3BB6266

Q35033140-28BA01D2-AB1F-4448-80AD-D0EC037CA5A4

Q35033140-6AFE7C5C-9A30-4CB5-BA44-1F90C84D5AE2

Q35033140-8B9421B8-F7E4-449E-9CFE-F29469E295D1

Q35033140-8D537508-9481-46FF-BBA9-E03292BD1D81

Q35033140-ADFB38EB-BFC3-4B19-821F-02BC9E4C2B0F

Q35033140-B6ECB1E9-549D-4C71-B30D-032B9C8EDC7F

Q35033140-E5A0B69D-D4FD-4EC3-95FB-606FF518F726

P2860

Q35033140-006C9ED4-3B28-46C6-B442-A30AC2CA95E8

Q35033140-009EE472-3FB7-452C-8D87-BE00FA731514

Q35033140-02254B11-4D80-4989-85C3-E609B29F20ED

Q35033140-0FADD6B3-48E4-43C3-9075-D10201FEA8F8

Q35033140-1DB1C375-2DB4-4FCC-9301-2DD515154B0F

Q35033140-1F42FE64-5E08-4486-9CC7-C9B5705B3F4D

Q35033140-2A8D9451-9E49-40FF-90E7-08E8DBF1A8D1

Q35033140-2EEF71B9-E4F2-4574-8F0E-0E931CA5C3BC

Q35033140-3980EBCF-38C4-4F49-841C-B5E89A628836

Q35033140-39F2B074-DBC6-41DA-BF0A-C39ED58EBFC6

P304

Q35033140-4DDED06E-9EFB-4800-A4C2-EA125C1FFC89

P31

Q35033140-93ABC784-31E1-4405-8025-23999AC0C4E2

P356

Q35033140-36193DD4-E65B-428A-A170-54D23EE6C9C5

P407

Q35033140-30B72603-43DE-418D-8A0A-11A5396E2AFB

P433

Q35033140-0A27A550-ABC8-4FC4-AB09-C9F0E3033F71

P478

Q35033140-F46EC468-56F9-488E-B73A-26881334759A

P577

Q35033140-D1E6B836-DF9E-4DDA-AB98-DE54255FCB1D

P5875

Q35033140-C0AED3DA-0B92-4EB6-A0AF-61938D6EB75B

P698

Q35033140-60F0B238-96A9-4505-ADD3-6F8AF4C10A57

P932

Q35033140-D539255F-B817-416C-B83B-9120924CB3C3

P356

PNAS.0600994103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

The Wilms tumor gene, Wt1, is ...... ture in the developing testis.

@en

P2093

Charlotte Lécureuil

http://www.w3.org/2001/XMLSchema#string

Fei Gao

http://www.w3.org/2001/XMLSchema#string

Florian Guillou

http://www.w3.org/2001/XMLSchema#string

Jian Min Deng

http://www.w3.org/2001/XMLSchema#string

Nargis Alam

http://www.w3.org/2001/XMLSchema#string

Richard R Behringer

http://www.w3.org/2001/XMLSchema#string

Sourindra Maiti

http://www.w3.org/2001/XMLSchema#string

Vicki Huff

http://www.w3.org/2001/XMLSchema#string

Zhen Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning and characterisation of the Sry-related transcription factor gene Sox8.

Requirement of Lim1 for female reproductive tract development

Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

Homozygous inactivation of Sox9 causes complete XY sex reversal in mice

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

P304

11987-11992

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0600994103

http://www.w3.org/2001/XMLSchema#string

P407

P433

32

http://www.w3.org/2001/XMLSchema#string

P478

103

http://www.w3.org/2001/XMLSchema#string

P577

2006-07-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6908176

http://www.w3.org/2001/XMLSchema#string

P698

16877546

http://www.w3.org/2001/XMLSchema#string

P932

1567685

http://www.w3.org/2001/XMLSchema#string