The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.
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Sex determination in the Squalius alburnoides complex: an initial characterization of sex cascade elements in the context of a hybrid polyploid genomeMolecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fishThe many facets of the Wilms' tumour gene, WT1Asynchronous expression of the homeodomain protein CUX1 in Sertoli cells and spermatids during spermatogenesis in mice.The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in miceLoss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testisEx vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation.Functional redundancy of TGF-beta family type I receptors and receptor-Smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse.WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal glandWt1 negatively regulates beta-catenin signaling during testis developmentThe Sertoli cell: one hundred fifty years of beauty and plasticity.Transcription and post-transcriptional regulation of spermatogenesis.Determination and stability of gonadal sexWilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation.Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell nicheExpression of inhibin-alpha is regulated synergistically by Wilms' tumor gene 1 (Wt1) and steroidogenic factor-1 (Sf1) in sertoli cells.Up-regulation of SOX9 in sertoli cells from testiculopathic patients accounts for increasing anti-mullerian hormone expression via impaired androgen receptor signalingThe Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome.Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene.Altered lipid homeostasis in Sertoli cells stressed by mild hyperthermia.Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablationPrmt5 is required for germ cell survival during spermatogenesis in mice.Wilms' tumor protein Wt1 is an activator of the anti-Müllerian hormone receptor gene Amhr2.Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in miceCorrect dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice.Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis.Insulin-Like Growth Factor 1 Receptor-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury.Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.Monitoring therapy with MEK inhibitor U0126 in a novel Wilms tumor model in Wt1 knockout Igf2 transgenic mice using 18F-FDG PET with dual-contrast enhanced CT and MRI: early metabolic response without inhibition of tumor growth.Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids.The molecular and cellular basis of gonadal sex reversal in mice and humans.Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional targetNephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation.Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis.Overactive beta-catenin signaling causes testicular sertoli cell tumor development in the mouse
P2860
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P2860
The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.
description
2006 nî lūn-bûn
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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@ast
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@en
type
label
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@ast
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@en
prefLabel
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@ast
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@en
P2093
P2860
P356
P1476
The Wilms tumor gene, Wt1, is ...... ture in the developing testis.
@en
P2093
Charlotte Lécureuil
Florian Guillou
Jian Min Deng
Nargis Alam
Richard R Behringer
Sourindra Maiti
Vicki Huff
Zhen Zhang
P2860
P304
11987-11992
P356
10.1073/PNAS.0600994103
P407
P577
2006-07-28T00:00:00Z