High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.
about
Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shiftAdditive effects of cherlerythrine chloride combination with erlotinib in human non-small cell lung cancer cells.Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells.Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy.Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches.Targeting protein homeostasis with nelfinavir/salinomycin dual therapy effectively induces death of mTORC1 hyperactive cells.p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole.Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA).
P2860
Q26999365-5EBBF810-BB4E-488C-A802-2C1D86409412Q33554429-A86C969B-2AA5-4A4B-B859-E1329D0F017EQ37698838-BA5B3778-5138-4251-89C9-9576E5236944Q38881119-E0B3F008-1EF7-4DE7-971C-386A6E25D630Q38994919-0E69105E-1E0C-4EF1-8C05-C7B6BAD3D8B2Q41472073-3FCDD8E0-0D78-4EF1-AC49-5E84B74BFCADQ45946958-902D10E4-32AB-46D2-9C6B-453A01C9F543Q47404654-92EC1342-8443-4A80-9F5B-97C3EDDB836FQ48112569-EA1BF967-1373-4742-BB21-F6A6942FF3A1Q48221452-54009EB0-B95A-4110-BCBA-89CC6505D147
P2860
High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
High-throughput drug screen id ...... death in a TSC2-null setting.
@ast
High-throughput drug screen id ...... death in a TSC2-null setting.
@en
type
label
High-throughput drug screen id ...... death in a TSC2-null setting.
@ast
High-throughput drug screen id ...... death in a TSC2-null setting.
@en
prefLabel
High-throughput drug screen id ...... death in a TSC2-null setting.
@ast
High-throughput drug screen id ...... death in a TSC2-null setting.
@en
P2093
P2860
P1476
High-throughput drug screen id ...... f death in a TSC2-null setting
@en
P2093
Carmen Priolo
Chenggang Li
Damir Khabibullin
Doug Medvetz
Elizabeth P Henske
John M Asara
Murugabaskar Balan
Soumitro Pal
P2860
P356
10.1158/1541-7786.MCR-14-0440
P577
2014-09-03T00:00:00Z