Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs. - Wikidata - wikimedia - TriplyDB

Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs.

Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs.

http://www.wikidata.org/entity/Q35034959

about

Diversity of intervertebral disc cells: phenotype and function Is the spinal motion segment a diarthrodial polyaxial joint: what a nice nucleus like you doing in a joint like this?Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro Mechanotransduction in intervertebral discs Foxa1 and Foxa2 are required for formation of the intervertebral discs 'Monster… -omics': on segmentation, re-segmentation, and vertebrae formation in amphibians and other vertebrates Notochordal cell-derived therapeutic strategies for discogenic back pain.Notochord to Nucleus Pulposus Transition.Putative oncogene Brachyury (T) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT.Chondrocyte-Specific Knockout of TSC-1 Leads to Congenital Spinal Deformity in Mice.Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc.Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth.Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.Transcriptome sequencing of Atlantic salmon (Salmo salar L.) notochord prior to development of the vertebrae provides clues to regulation of positional fate, chordoblast lineage and mineralisation Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc.Sonic hedgehog in the notochord is sufficient for patterning of the intervertebral discs Nucleus pulposus phenotypic markers to determine stem cell differentiation: fact or fiction?N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.Cell signaling pathways related to pain receptors in the degenerated disk.Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development.Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm.Bridging the Gap: Understanding Embryonic Intervertebral Disc Development Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies.Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?The notochord: structure and functions.Stem Cells in Skeletal Tissue Engineering: Technologies and Models.Regulation of human nucleus pulposus cells by peptide-coupled substrates.Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid.Notochord Cells in Intervertebral Disc Development and Degeneration Signaling networks in joint development.Surgical anatomy, radiological features, and molecular biology of the lumbar intervertebral discs.Developmental mechanisms of intervertebral disc and vertebral column formation.Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus.Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells.The role of the notochord in amniote vertebral column segmentation.Spine Patterning Is Guided by Segmentation of the Notochord Sheath.

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P2860

Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs.

http://www.wikidata.org/entity/Q35034959

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Hedgehog signaling is required ...... thin the intervertebral discs.

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Hedgehog signaling is required ...... thin the intervertebral discs.

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type

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Hedgehog signaling is required ...... thin the intervertebral discs.

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Hedgehog signaling is required ...... thin the intervertebral discs.

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Hedgehog signaling is required ...... thin the intervertebral discs.

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Hedgehog signaling is required ...... thin the intervertebral discs.

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Hedgehog signaling is required ...... thin the intervertebral discs.

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Brian D Harfe

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Kyung-Suk Choi

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P2860

Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation

Generalized lacZ expression with the ROSA26 Cre reporter strain

Stages of embryonic development of the zebrafish

Sonic hedgehog regulates growth and morphogenesis of the tooth

Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways

Hedgehog signaling in animal development: paradigms and principles

Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation

Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Collagen II is essential for the removal of the notochord and the formation of intervertebral discs

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