The butterfly effect in cancer: a single base mutation can remodel the cell.
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The Quest for Targets Executing MYC-Dependent Cell TransformationEvolutionary determinants of cancerThe isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation.NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability.HER2 missense mutations have distinct effects on oncogenic signaling and migration.Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare MutationsPerturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop.Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal CarcinomasA microscopic landscape of the invasive breast cancer genomeIn B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signalingMetabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line.Proteomics in the genome engineering era.Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.Effects of TP53 and PIK3CA mutations in early breast cancer: a matter of co-mutation and tumor-infiltrating lymphocytes.A butterfly effect in cancer.The effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS).Energetic redistribution in allostery to execute protein function.
P2860
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P2860
The butterfly effect in cancer: a single base mutation can remodel the cell.
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2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2015 թվականի հունվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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The butterfly effect in cancer: a single base mutation can remodel the cell.
@ast
The butterfly effect in cancer: a single base mutation can remodel the cell.
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type
label
The butterfly effect in cancer: a single base mutation can remodel the cell.
@ast
The butterfly effect in cancer: a single base mutation can remodel the cell.
@en
prefLabel
The butterfly effect in cancer: a single base mutation can remodel the cell.
@ast
The butterfly effect in cancer: a single base mutation can remodel the cell.
@en
P2093
P2860
P50
P356
P1476
The butterfly effect in cancer: a single base mutation can remodel the cell.
@en
P2093
John R Yates
Lujian Liao
Marloes Jonkers
P2860
P304
P356
10.1073/PNAS.1424012112
P407
P577
2015-01-12T00:00:00Z