High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
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High Content Imaging (HCI) on Miniaturized Three-Dimensional (3D) Cell CulturesStem cell-derived liver cells for drug testing and disease modelingAdvances in Engineered Liver Models for Investigating Drug-Induced Liver InjuryBuilding a robust 21st century chemical testing program at the U.S. Environmental Protection Agency: recommendations for strengthening scientific engagementA chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternativesPatient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicityPluripotent stem cells: the last 10 years.Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes.High-content assays for characterizing the viability and morphology of 3D cancer spheroid cultures.Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells.A shift in paradigm towards human biology-based systems for cholestatic-liver diseases.The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.Toxicity testing and drug screening using iPSC-derived hepatocytes, cardiomyocytes, and neural cells.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.Using high-content screening technology for studying drug-induced hepatotoxicity in preclinical studies.Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis.High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and HepatocytesHigh-content high-throughput assays for characterizing the viability and morphology of human iPSC-derived neuronal cultures.Prospects and Frontiers of Stem Cell ToxicologyTools to Measure Cell Health and Cytotoxicity Using High Content Imaging and Analysis.CRISPR/CAS9-mediated Tspo gene mutations lead to reduced mitochondrial membrane potential and STEROID FORMation in MA-10 mouse tumor Leydig cells.Pluripotent Stem Cell-Derived Human Tissue: Platforms to Evaluate Drug Metabolism and Safety.SLAS Europe High-Content Screening Conference in Dresden: A Glimpse of the Future?Human induced pluripotent stem cell-derived hepatocytes for toxicology testing.Comparison of hepatic 2D sandwich cultures and 3D spheroids for long-term toxicity applications: A multi-center study.The Need for, and the Role of the Toxicological Chemist in the Design of Safer Chemicals.Hepatic differentiation of human adipose tissue-derived mesenchymal stem cells and adverse effects of arsanilic acid and acetaminophen during in vitro hepatic developmental stage.A transcriptomic study suggesting human iPSC-derived hepatocytes potentially offer a better in vitro model of hepatotoxicity than most hepatoma cell lines.Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes.Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions.Drug-induced steatohepatitisA nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosisModels of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives
P2860
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P2860
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
@en
type
label
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
@en
prefLabel
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
@en
P2093
P2860
P356
P1476
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
@en
P2093
Evan F Cromwell
Ivan Rusyn
Jayne Hesley
Oksana Sirenko
P2860
P356
10.1089/ADT.2013.520
P577
2013-11-14T00:00:00Z