Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells.
about
Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondriaThe malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cellsMathematical model of metabolism and electrophysiology of amino acid and glucose stimulated insulin secretion: in vitro validation using a β-cell lineTaurine regulates insulin release from pancreatic beta cell lines.Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.Mitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role?Mitochondrial transporters as novel targets for intracellular calcium signaling.Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells.Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction.Mitochondrial dynamics and morphology in beta-cells.Reactive aldehydes--second messengers of free radicals in diabetes mellitus.Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition.Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies.Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism.Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion.Modulation of [Ca2+]i signaling dynamics and metabolism by perinuclear mitochondria in mouse parotid acinar cells.Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus.Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells.Cell culture models of fatty acid overload: Problems and solutions.Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release.
P2860
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P2860
Mitochondria as the conductor of metabolic signals for insulin exocytosis in pancreatic beta-cells.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Mitochondria as the conductor ...... osis in pancreatic beta-cells.
@en
type
label
Mitochondria as the conductor ...... osis in pancreatic beta-cells.
@en
prefLabel
Mitochondria as the conductor ...... osis in pancreatic beta-cells.
@en
P356
P1476
Mitochondria as the conductor ...... tosis in pancreatic beta-cells
@en
P2093
Maechler P
P2888
P304
P356
10.1007/PL00012507
P577
2002-11-01T00:00:00Z