Familial hypertrophic cardiomyopathy related cardiac troponin C L29Q mutation alters length-dependent activation and functional effects of phosphomimetic troponin I*
about
Cardiac Troponin and Tropomyosin: Structural and Cellular Perspectives to Unveil the Hypertrophic Cardiomyopathy PhenotypeWhy Is there a Limit to the Changes in Myofilament Ca2+-Sensitivity Associated with Myopathy Causing Mutations?Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugsInvestigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy.Uncoupling of myofilament Ca2+ sensitivity from troponin I phosphorylation by mutations can be reversed by epigallocatechin-3-gallate.Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation.Biochemical characterisation of Troponin C mutations causing hypertrophic and dilated cardiomyopathies.Changes in the dynamics of the cardiac troponin C molecule explain the effects of Ca2+-sensitizing mutations.The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29QCharacterization of Zebrafish Cardiac and Slow Skeletal Troponin C Paralogs by MD Simulation and ITC.
P2860
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P2860
Familial hypertrophic cardiomyopathy related cardiac troponin C L29Q mutation alters length-dependent activation and functional effects of phosphomimetic troponin I*
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Familial hypertrophic cardiomy ...... of phosphomimetic troponin I*
@en
type
label
Familial hypertrophic cardiomy ...... of phosphomimetic troponin I*
@en
prefLabel
Familial hypertrophic cardiomy ...... of phosphomimetic troponin I*
@en
P2093
P2860
P1433
P1476
Familial hypertrophic cardiomy ...... of phosphomimetic troponin I*
@en
P2093
Alison Y Li
Jonathan Davis
Kaveh Rayani
Sean Little
P2860
P304
P356
10.1371/JOURNAL.PONE.0079363
P407
P577
2013-11-18T00:00:00Z