A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity - Wikidata - wikimedia - TriplyDB

A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity

A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity

http://www.wikidata.org/entity/Q35048852

about

Regulation of miRNA transcription in macrophages in response to Candida albicans NF-kappaB Signaling in Chronic Inflammatory Airway Disease Treatment of allergic asthma: modulation of Th2 cells and their responses Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades IKKα contributes to canonical NF-κB activation downstream of Nod1-mediated peptidoglycan recognition Addressing reported pro-apoptotic functions of NF-kappaB: targeted inhibition of canonical NF-kappaB enhances the apoptotic effects of doxorubicin Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia Inhibition of IkappaB kinase-beta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity Inhibition of the nuclear factor-κB pathway prevents beta cell failure and diet induced diabetes in Psammomys obesus Synthetic response of stimulated respiratory epithelium: modulation by prednisolone and iKK2 inhibition.IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance.IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity.Overexpression of receptor for advanced glycation end products and high-mobility group box 1 in human dental pulp inflammation.IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy.The myxobacterial compounds spirangien a and spirangien M522 are potent inhibitors of IL-8 expression.Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo.Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease.Towards the small and the beautiful: a small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway.Inhibition of IκB kinase (IKK) protects against peripheral nerve dysfunction of experimental diabetes.Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.IKK biology.Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo Nuclear factor kappa B induction in airway epithelium increases lung inflammation in allergen-challenged mice.IKK phosphorylation of NF-κB at serine 536 contributes to acquired cisplatin resistance in head and neck squamous cell cancer The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.Differential IKK/NF-κB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells.Retinoic acid modulates chromatin to potentiate tumor necrosis factor alpha signaling on the DIF2 promoter (R)-albuterol decreases immune responses: role of activated T cells Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.Reovirus activates a caspase-independent cell death pathway.Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function Inhibitor of NFκB Kinase Subunit 2 Blockade Hinders the Initiation but Aggravates the Progression of Crescentic GN Targeting IκB Kinase β/NF-κB Signaling in Human Prostate Cancer by a Novel IκB Kinase β Inhibitor CmpdA.Cell-penetrating peptides and proteins: new inhibitors of allergic airways disease.Kinase inhibitors for the treatment of inflammatory and autoimmune disorders.

P2860

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P2860

A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity

http://www.wikidata.org/entity/Q35048852

description

2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

A selective novel low-molecula ...... oad anti-inflammatory activity

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A selective novel low-molecula ...... oad anti-inflammatory activity

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type

label

A selective novel low-molecula ...... oad anti-inflammatory activity

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A selective novel low-molecula ...... oad anti-inflammatory activity

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prefLabel

A selective novel low-molecula ...... oad anti-inflammatory activity

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A selective novel low-molecula ...... oad anti-inflammatory activity

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P1433

British Journal of Pharmacology

P1476

A selective novel low-molecula ...... oad anti-inflammatory activity

@en

P2093

Aaron Berlin

http://www.w3.org/2001/XMLSchema#string

Florian Gantner

http://www.w3.org/2001/XMLSchema#string

Hiroshi Komura

http://www.w3.org/2001/XMLSchema#string

Hisayo Inbe

http://www.w3.org/2001/XMLSchema#string

Karl Ziegelbauer

http://www.w3.org/2001/XMLSchema#string

Katsuya Sakai

http://www.w3.org/2001/XMLSchema#string

Keisuke Takeshita

http://www.w3.org/2001/XMLSchema#string

Kevin B Bacon

http://www.w3.org/2001/XMLSchema#string

Kinji Fuchikami

http://www.w3.org/2001/XMLSchema#string

Mina Ishimori

http://www.w3.org/2001/XMLSchema#string

P2860

IKK2 inhibitor alleviates kidney and wasting diseases in a murine model of human AIDS

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway inflammation

IkappaB kinase signaling is essential for maintenance of mature B cells

Missing pieces in the NF-kappaB puzzle

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity.

Proteasome inhibition: A novel mechanism to combat asthma.

Mechanisms of eosinophil-associated inflammation.

P304

178-192

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scholarly article

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10.1038/SJ.BJP.0706176

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P407

P433

2

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P478

145

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P577

2005-05-01T00:00:00Z

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7980192

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15753951

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1576128

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