Essential fatty acid synthesis and its regulation in mammals.
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FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island populationGenetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational studyAbnormal n-6 fatty acid metabolism in cystic fibrosis is caused by activation of AMP-activated protein kinaseQuantitative contributions of diet and liver synthesis to docosahexaenoic acid homeostasis.Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research.Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats.Can the rat liver maintain normal brain DHA metabolism in the absence of dietary DHA?Abnormal unsaturated fatty acid metabolism in cystic fibrosis: biochemical mechanisms and clinical implications.Docosahexaenoic acid: brain accretion and roles in neuroprotection after brain hypoxia and ischemiaInhibiting delta-6 desaturase activity suppresses tumor growth in mice.Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.Expression of genes controlling fat deposition in two genetically diverse beef cattle breeds fed high or low silage diets.Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th centuryTopology and static response of interaction networks in molecular biologyDHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity.Dietary n-6 polyunsaturated fatty acid deprivation increases docosahexaenoic acid metabolism in rat brain.Increased ω6-Containing Phospholipids and Primary ω6 Oxidation Products in the Brain Tissue of Rats on an ω3-Deficient DietDifferences in the skeletal muscle transcriptome profile associated with extreme values of fatty acids contentIntegrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism.A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate.Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male ratsTargeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trialWhole-body synthesis secretion of docosahexaenoic acid from circulating eicosapentaenoic acid in unanesthetized rats.Regulation of FADS2 transcription by SREBP-1 and PPAR-α influences LC-PUFA biosynthesis in fish.Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice.Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed miceSupplementation of glycerol or fructose via drinking water to grazing lambs on tissue glycogen level and lipogenesis.Delayed production of arachidonic acid contributes to the delay of proteinase-activated receptor-1 (PAR1)-triggered prostaglandin E2 release in rat gastric epithelial RGM1 cells.Regulation of desaturase expression in HL60 cells.Regulation of tissue LC-PUFA contents, Δ6 fatty acyl desaturase (FADS2) gene expression and the methylation of the putative FADS2 gene promoter by different dietary fatty acid profiles in Japanese seabass (Lateolabrax japonicus).Quantitative Profiling of Hydroxy Lipid Metabolites in Mouse Organs Reveals Distinct Lipidomic Profiles and Modifications Due to Elevated n-3 Fatty Acid Levels.Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse.Metabolism and functions of docosahexaenoic acid-containing membrane glycerophospholipids.Breed and dietary linseed affect gene expression of enzymes and transcription factors involved in n-3 long chain polyunsaturated fatty acids synthesis in longissimus thoracis muscle of bulls.Dietary arachidonate differentially alters desaturase-elongase pathway flux and gene expression in liver and intestine of suckling pigs.Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice.Compartmental modeling to quantify alpha-linolenic acid conversion after longer term intake of multiple tracer boluses.Rat heart cannot synthesize docosahexaenoic acid from circulating alpha-linolenic acid because it lacks elongase-2.Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism.
P2860
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P2860
Essential fatty acid synthesis and its regulation in mammals.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Essential fatty acid synthesis and its regulation in mammals.
@ast
Essential fatty acid synthesis and its regulation in mammals.
@en
type
label
Essential fatty acid synthesis and its regulation in mammals.
@ast
Essential fatty acid synthesis and its regulation in mammals.
@en
prefLabel
Essential fatty acid synthesis and its regulation in mammals.
@ast
Essential fatty acid synthesis and its regulation in mammals.
@en
P1476
Essential fatty acid synthesis and its regulation in mammals.
@en
P2093
P304
P356
10.1016/S0952-3278(02)00264-8
P577
2003-02-01T00:00:00Z