Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
about
C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancerDeregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerPATZ1 gene has a critical role in the spermatogenesis and testicular tumoursInhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer.PAI-1 leads to G1-phase cell-cycle progression through cyclin D3/cdk4/6 upregulationFOXO1A is a target for HER2-overexpressing breast tumors.miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cellsAnnexin A10 in human oral cancer: biomarker for tumoral growth via G1/S transition by targeting MAPK signaling pathwaysCytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma.Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism.p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.Somatic mutation and germline sequence abnormalities in CDKN1B, encoding p27Kip1, in sporadic parathyroid adenomasComplex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localizationThe thyroid hormone receptors as modulators of skin proliferation and inflammationANGPTL3 is a novel biomarker as it activates ERK/MAPK pathway in oral cancer.A crosstalk imbalance between p27(Kip1) and its interacting molecules enhances breast carcinogenesisImmunoexpression status and prognostic value of mTOR and hypoxia-induced pathway members in primary and metastatic clear cell renal cell carcinomas.Mutant AKT1-E17K is oncogenic in lung epithelial cellsExpression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy.Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo.Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activityDysregulation of mammalian target of rapamycin pathway in plasmacytoid variant of urothelial carcinoma of the urinary bladderTGF-beta through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formationPin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process.Prognostic and predictive value of cell cycle deregulation in non-small-cell lung cancer.LIM domain only 2 induces glioma invasion via cytosolic p27(KIP1).MicroRNA miR-24 promotes cell proliferation by targeting the CDKs inhibitors p27Kip1 and p16INK4a.TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).Upregulated p27kip1 can downregulate survivin expression and inhibit telomerase activity in gastric carcinoma cells.Transcriptional downregulation of p27KIP1 through regulation of E2F function during LMP1-mediated transformation.RNA interference-mediated knockdown of p21(WAF1) enhances anti-tumor cell activity of oncolytic adenoviruses.Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.The ID proteins contribute to the growth of rodent fibroblasts during LMP1-mediated transformation.Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: implications for prostate cancer chemoprevention.Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma.Akt signalling parameters are different in oncocytomas compared to renal cell carcinoma.Prognostic relevance of the mTOR pathway in renal cell carcinoma: implications for molecular patient selection for targeted therapy.Val1483Ile in FASN gene is linked to central obesity and insulin sensitivity in adult white men.The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner.
P2860
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P2860
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
description
2002 nî lūn-bûn
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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@ast
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@en
type
label
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@ast
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@en
prefLabel
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@ast
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@en
P2093
P356
P1433
P1476
Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.
@en
P2093
Alfredo Fusco
Giuseppe Viglietto
Maria Letizia Motti
P304
P356
10.4161/CC.1.6.263
P577
2002-11-01T00:00:00Z