Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor - Wikidata - wikimedia - TriplyDB

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor

http://www.wikidata.org/entity/Q35057027

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Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2 Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) i Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties Protein-arginine deiminase 2 suppresses proliferation of colon cancer cells through protein citrullination Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration A FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs.Peptidylarginine deiminase 4 contributes to tumor necrosis factor α-induced inflammatory arthritis.Potential role for PADI-mediated histone citrullination in preimplantation development Peptidyl arginine deiminase-4 activation exacerbates kidney ischemia-reperfusion injury.Identification of PADI2 as a potential breast cancer biomarker and therapeutic target.Epigenetics of autoantigens: new opportunities for therapy of autoimmune diseases.Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.Inhibiting protein arginine deiminases has antioxidant consequences.Chemical biology of protein arginine modifications in epigenetic regulation Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice.Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis.Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen.Activation of PAD4 in NET formation.Chemical Proteomic Platform To Identify Citrullinated Proteins Detection and identification of protein citrullination in complex biological systems Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer Extracellular traps and macrophages: new roles for the versatile phagocyte.Protein Arginine Methylation and Citrullination in Epigenetic Regulation Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus Peptidylarginine Deiminase Inhibitor Suppresses Neutrophil Extracellular Trap Formation and MPO-ANCA Production Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation.Citrullination of glial intermediate filaments is an early response in retinal injury Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds.Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway.Enhanced formation and disordered regulation of NETs in myeloperoxidase-ANCA-associated microscopic polyangiitis.The protein arginine deiminases: Structure, function, inhibition, and disease.

P2860

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P2860

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor

http://www.wikidata.org/entity/Q35057027

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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Suppression of colitis in mice ...... ylarginine deiminase inhibitor

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Suppression of colitis in mice ...... ylarginine deiminase inhibitor

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Suppression of colitis in mice ...... ylarginine deiminase inhibitor

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Suppression of colitis in mice ...... ylarginine deiminase inhibitor

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Suppression of colitis in mice ...... ylarginine deiminase inhibitor

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AJPGI.00435.2010

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American Journal of Physiology - Gastrointestinal and Liver Physiology

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Suppression of colitis in mice ...... ylarginine deiminase inhibitor

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Alena P Chumanevich

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Alexander A Chumanevich

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Bryan A Knuckley

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Corey P Causey

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Deepak Poudyal

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Justin E Jones

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Lorne J Hofseth

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Lydia E Matesic

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Paul R Thompson

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Tia Davis

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P2860

Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis

The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis

Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis

Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis

Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors

Dose translation from animal to human studies revisited

Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.

Increased PADI4 expression in blood and tissues of patients with malignant tumors

American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells.

Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis.

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10.1152/AJPGI.00435.2010

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6

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300

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50420186

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21415415

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