The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models.
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Context Sensitive Modeling of Cancer Drug SensitivityA bispecific enediyne-energized fusion protein targeting both epidermal growth factor receptor and insulin-like growth factor 1 receptor showing enhanced antitumor efficacy against non-small cell lung cancerReduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab.Inhibition of p70S6K1 Activation by Pdcd4 Overcomes the Resistance to an IGF-1R/IR Inhibitor in Colon Carcinoma Cells.Enhancement of doxorubicin cytotoxicity of human cancer cells by tyrosine kinase inhibition of insulin receptor and type I IGF receptorEmerging therapies in pancreas cancer.IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomidePhase I study of humanized monoclonal antibody AVE1642 directed against the type 1 insulin-like growth factor receptor (IGF-1R), administered in combination with anticancer therapies to patients with advanced solid tumors.Targeting the insulin-like growth factor-1 receptor in human cancer.MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.Insulin-like growth factor: current concepts and new developments in cancer therapy.Insulin-like growth factor 1 regulates growth of endometrial carcinoma through PI3k signaling pathway in insulin-resistant type 2 diabetesOvary ecdysteroidogenic hormone functions independently of the insulin receptor in the yellow fever mosquito, Aedes aegyptiOxaliplatin in the era of personalized medicine: from mechanistic studies to clinical efficacy.A comprehensive pharmacokinetic/pharmacodynamics analysis of the novel IGF1R/INSR inhibitor BI 893923 applying in vitro, in vivo and in silico modeling techniques.IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination.Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer.
P2860
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P2860
The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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name
The insulin-like growth factor ...... inst colorectal cancer models.
@ast
The insulin-like growth factor ...... inst colorectal cancer models.
@en
type
label
The insulin-like growth factor ...... inst colorectal cancer models.
@ast
The insulin-like growth factor ...... inst colorectal cancer models.
@en
prefLabel
The insulin-like growth factor ...... inst colorectal cancer models.
@ast
The insulin-like growth factor ...... inst colorectal cancer models.
@en
P2093
P2860
P921
P1476
The insulin-like growth factor ...... inst colorectal cancer models.
@en
P2093
Aik Choon Tan
Andrew Thorburn
John J Tentler
S Gail Eckhardt
Sara A Flanigan
Stephen Leong
Todd M Pitts
P2860
P304
P356
10.1158/1078-0432.CCR-10-2054
P407
P577
2010-10-13T00:00:00Z