Topoisomerase I inhibitors, shikonin and topotecan, inhibit growth and induce apoptosis of glioma cells and glioma stem cells.

Topoisomerase I inhibitors, shikonin and topotecan, inhibit growth and induce apoptosis of glioma cells and glioma stem cells.

Item
http://www.wikidata.org/entity/Q35058674
Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plantsIn vitro induction of erythrocyte phosphatidylserine translocation by the natural naphthoquinone shikonin.Apoptotic death of cancer stem cells for cancer therapy.MiR-330-mediated regulation of SH3GL2 expression enhances malignant behaviors of glioblastoma stem cells by activating ERK and PI3K/AKT signaling pathwaysShikonin Isolated from Lithospermum erythrorhizon Downregulates Proinflammatory Mediators in Lipopolysaccharide-Stimulated BV2 Microglial Cells by Suppressing Crosstalk between Reactive Oxygen Species and NF-κB.All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damagePotent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer.Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents.Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal MedicineShikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway.Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells.Decreased adiposity and enhanced glucose tolerance in shikonin treated mice.Research on human glioma stem cells in China.Shikonin inhibits myeloid differentiation protein-2 to prevent lipopolysaccharide-induced acute lung injury.Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition.Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway.Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
P2860

Topoisomerase I inhibitors, shikonin and topotecan, inhibit growth and induce apoptosis of glioma cells and glioma stem cells.

Item
http://www.wikidata.org/entity/Q35058674
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@ast
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@en
type
label
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@ast
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@en
prefLabel
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@ast
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Topoisomerase I inhibitors, sh ...... a cells and glioma stem cells.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0081815
P407
P433
P478
P577
P5875
P698
P932