Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation. - Wikidata - wikimedia - TriplyDB

Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

http://www.wikidata.org/entity/Q35063220

about

Klotho, phosphate and inflammation/ageing in chronic kidney disease Klotho: a humeral mediator in CSF and plasma that influences longevity and susceptibility to multiple complex disorders, including depression NFκB-sensitive Orai1 expression in the regulation of FGF23 release.The sound of health.Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism Sirt6 deficiency results in progression of glomerular injury in the kidney Soluble α-klotho as a novel biomarker in the early stage of nephropathy in patients with type 2 diabetes α-Klotho protects against oxidative damage in pulmonary epithelia.Small-molecule Klotho enhancers as novel treatment of neurodegeneration.A polymeric nanomedicine diminishes inflammatory events in renal tubular cells Risk of ESRD and all cause mortality in type 2 diabetes according to circulating levels of FGF-23 and TNFR1.Klotho gene deficiency causes salt-sensitive hypertension via monocyte chemotactic protein-1/CC chemokine receptor 2-mediated inflammation.Renal expression of FGF23 in progressive renal disease of diabetes and the effect of ACE inhibitor The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody Klotho suppresses cardiomyocyte apoptosis in mice with stress-induced cardiac injury via downregulation of endoplasmic reticulum stress.Decreased circulating klotho levels in patients undergoing dialysis and relationship to oxidative stress and inflammation Dose-dependent effects of morphine exposure on mRNA and microRNA (miR) expression in hippocampus of stressed neonatal mice.The role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy.Altered KLOTHO and NF-κB-TNF-α Signaling Are Correlated with Nephrectomy-Induced Cognitive Impairment in Rats.Klotho gene delivery ameliorates renal hypertrophy and fibrosis in streptozotocin-induced diabetic rats by suppressing the Rho-associated coiled-coil kinase signaling pathway.Myocardin-Related Transcription Factor A Epigenetically Regulates Renal Fibrosis in Diabetic Nephropathy.Longevity factor klotho and chronic psychological stress Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells The emerging role of Klotho in clinical nephrology.Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury Klotho Reduction in Alveolar Macrophages Contributes to Cigarette Smoke Extract-induced Inflammation in Chronic Obstructive Pulmonary Disease.Klotho Ameliorates Kidney Injury and Fibrosis and Normalizes Blood Pressure by Targeting the Renin-Angiotensin System.Renal and extrarenal actions of Klotho.Klotho Contributes to Pravastatin Effect on Suppressing IL-6 Production in Endothelial Cells.The role of fibroblast growth factor 23 and Klotho in uremic cardiomyopathy.The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.Concentrations of fetuin-A, osteoprotegerin and α-Klotho in patients with alcoholic liver cirrhosis.Negative regulation of NF-κB p65 activity by serine 536 phosphorylation Klotho and chronic kidney disease.Key pathways in renal disease progression of experimental diabetes.Association between Soluble Klotho and Change in Kidney Function: The Health Aging and Body Composition Study.Klotho, the Holy Grail of the kidney: from salt sensitivity to chronic kidney disease.Klotho Prevents NFκB Translocation and Protects Endothelial Cell From Senescence Induced by Uremia.Effects of klotho deletion from bone during chronic kidney disease.Calcineurin inhibitors cyclosporine A and tacrolimus induce vascular inflammation and endothelial activation through TLR4 signaling.

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P2860

Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

http://www.wikidata.org/entity/Q35063220

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Klotho depletion contributes t ...... A (serine)536 phosphorylation.

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Klotho depletion contributes t ...... A (serine)536 phosphorylation.

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Klotho depletion contributes t ...... A (serine)536 phosphorylation.

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Klotho depletion contributes t ...... A (serine)536 phosphorylation.

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Klotho depletion contributes t ...... A (serine)536 phosphorylation.

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Klotho depletion contributes t ...... A (serine)536 phosphorylation.

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Klotho depletion contributes t ...... lA (serine)536 phosphorylation

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Kevin P Rosenblatt

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Nilay Dey

http://www.w3.org/2001/XMLSchema#string

Partha S Sarkar

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Reynolds Brobey

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Ronald G Tilton

http://www.w3.org/2001/XMLSchema#string

Srijita Banerjee

http://www.w3.org/2001/XMLSchema#string

Wanda S LeJeune

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Yanhua Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

Suppression of aging in mice by the hormone Klotho

Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2

Signaling to NF-kappaB

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

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1907-1916

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scholarly article

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10.2337/DB10-1262

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7

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60

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Sanjeev Choudhary

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2011-05-18T00:00:00Z

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51147228

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21593200

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phosphorylation

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3121423

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