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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

http://www.wikidata.org/entity/Q35063263

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The rise of regulatory RNA Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs The Promise and Challenge of Therapeutic MicroRNA Silencing in Diabetes and Metabolic Diseases β-Cell MicroRNAs: Small but Powerful MicroRNAs as pharmacological targets in diabetes Role of regulatory micro RNAs in type 2 diabetes mellitus-related inflammation Hypothalamic miRNAs: emerging roles in energy balance control Risk factors and primary prevention trials for type 1 diabetes Redox homeostasis in pancreatic β cells Gender and Obesity Specific MicroRNA Expression in Adipose Tissue from Lean and Obese Pigs MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice Increased microRNA-146a levels in plasma of patients with newly diagnosed type 2 diabetes mellitus miR-24 regulates menin in the endocrine pancreas Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis.MicroRNA Expression Varies according to Glucose Tolerance, Measurement Platform, and Biological Source.Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction.MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.The role of microRNAs in diabetic nephropathy.MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells.Exercise: putting action into our epigenome.Sepsis-induced acute lung injury (ALI) is milder in diabetic rats and correlates with impaired NFkB activation.Cell-free nucleic acids as non-invasive biomarkers of gynecological cancers, ovarian, endometrial and obstetric disorders and fetal aneuploidy.Transcriptome profiling of microRNA by Next-Gen deep sequencing reveals known and novel miRNA species in the lipid fraction of human breast milk Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.Genetics of type 2 diabetes-pitfalls and possibilities.Loss of miRNAs during processing and storage of cow's (Bos taurus) milk.Leucine alters hepatic glucose/lipid homeostasis via the myostatin-AMP-activated protein kinase pathway - potential implications for nonalcoholic fatty liver disease T2DM: Why Epigenetics?Stem cell approaches for diabetes: towards beta cell replacement.Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65.A simple matter of life and death-the trials of postnatal Beta-cell mass regulation The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells.MicroRNAs and diabetic complications The Role of Serum MicroRNA-6767-5p as a Biomarker for the Diagnosis of Polycystic Ovary Syndrome Association study of polymorphisms in miRNAs with T2DM in Chinese population.Gene regulation by dietary microRNAs.MicroRNA-613 represses lipogenesis in HepG2 cells by downregulating LXRα Human vascular endothelial cells transport foreign exosomes from cow's milk by endocytosis.Gender-dependent miR-375 promoter methylation and the risk of type 2 diabetes.miR-200a regulates Rheb-mediated amelioration of insulin resistance after duodenal-jejunal bypass.

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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

http://www.wikidata.org/entity/Q35063263

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

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MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications

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Ryan J Taft

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High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expression

The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

miR-375 enhances palmitate-induced lipoapoptosis in insulin-secreting NIT-1 cells by repressing myotrophin (V1) protein expression

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells

The microRNA signature in response to insulin reveals its implication in the transcriptional action of insulin in human skeletal muscle and the role of a sterol regulatory element-binding protein-1c/myocyte enhancer factor 2C pathway

miR-375 maintains normal pancreatic alpha- and beta-cell mass

Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

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1825-1831

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10.2337/DB11-0171

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Selene L Fernandez-Valverde

John S. Mattick

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endocrine system

complications of diabetes mellitus

physiological phenomena

Aizkuņģa dziedzeris

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3121441

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