Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors
about
Buried lysine, but not arginine, titrates and alters transmembrane helix tilt.Membrane environment modulates the pKa values of transmembrane helicesIdentifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels.Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore.Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin.NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChRNovel missense mutations in the glycine receptor β subunit gene (GLRB) in startle diseaseSyndromic deafness mutations at Asn 14 differentially alter the open stability of Cx26 hemichannels.Emerging approaches to probing ion channel structure and function.Molecular dissection of Cl--selective Cys-loop receptor points to components that are dispensable or essential for channel activity.Inhibitory mechanism of peptides with a repeating hydrophobic and hydrophilic residue pattern on interleukin-10.Approaching the 5-HT₃ receptor heterogeneity by computational studies of the transmembrane and intracellular domains.
P2860
Q30533993-6BFE6801-DFDA-4939-882A-4DF8E259DF47Q30903257-44CE5DE0-C042-4D7F-BE80-4DC197B599E7Q33364168-DA45CBA9-48CC-4B65-B5D9-BBA34F0BC502Q35145307-81050862-C49D-4B4D-8113-68013EB4C363Q35862414-1A54EBD7-8B39-4591-9BF0-7F30CF3ECA69Q35937704-4193C51C-D861-401F-8A34-DBB1FA85F49EQ36501779-969ABD8B-F927-41C4-909D-E7993443402CQ36636926-B4A4069C-0CE8-4894-961E-C91C7D9DF411Q37047097-482D3782-5F33-41D7-AB48-4C1360871B3FQ38029528-F15A2337-032A-47A3-9B57-86725F25F958Q39936711-57BE36E2-E04D-42C5-BFC8-83F495489BA3Q40522418-4F05B481-C912-478D-943C-39675A01BF3EQ44178393-22C8CF99-01C1-4EDA-A709-E6F79917FCB9
P2860
Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@ast
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@en
type
label
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@ast
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@en
prefLabel
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@ast
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@en
P2860
P356
P1433
P1476
Tunable pKa values and the bas ...... es in nicotinic-type receptors
@en
P2093
Gisela D Cymes
P2860
P2888
P304
P356
10.1038/NATURE10015
P407
P577
2011-05-22T00:00:00Z
P5875
P6179
1018992718