A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease.

A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease.

Item
http://www.wikidata.org/entity/Q35064636
A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.A rationally designed small molecule for identifying an in vivo link between metal-amyloid-β complexes and the pathogenesis of Alzheimer's disease.New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.Inhibitory effects of magnolol and honokiol on human calcitonin aggregation.A High Affinity Red Fluorescence and Colorimetric Probe for Amyloid β Aggregates.Ultraviolet light triggers the conversion of Cu2+-bound Aβ42 aggregates into cytotoxic species in a copper chelation-independent manner.Modeling the Aggregation Propensity and Toxicity of Amyloid-β Variants.How Zn can impede Cu detoxification by chelating agents in Alzheimer's disease: a proof-of-concept study.Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease.Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease.Role of Copper in the Onset of Alzheimer's Disease Compared to Other Metals.(R)-α-trifluoromethylalanine containing short peptide in the inhibition of amyloid peptide fibrillationEffects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation
P2860

A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-β implicated in Alzheimer's disease.

Item
http://www.wikidata.org/entity/Q35064636
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A small molecule that displays ...... icated in Alzheimer's disease.
@ast
A small molecule that displays ...... icated in Alzheimer's disease.
@en
type
label
A small molecule that displays ...... icated in Alzheimer's disease.
@ast
A small molecule that displays ...... icated in Alzheimer's disease.
@en
prefLabel
A small molecule that displays ...... icated in Alzheimer's disease.
@ast
A small molecule that displays ...... icated in Alzheimer's disease.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
A small molecule that displays ...... icated in Alzheimer's disease.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932