In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
about
Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ERStructure of the Sec61 channel opened by a signal sequenceThe mechanism of membrane-associated steps in tail-anchored protein insertionListerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociationReconstitution of a minimal ribosome-associated ubiquitination pathway with purified factorsCompartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo.Protein targeting and degradation are coupled for elimination of mislocalized proteins.The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.Translation elongation regulates substrate selection by the signal recognition particle.Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections.Secretory protein profiling reveals TNF-α inactivation by selective and promiscuous Sec61 modulators.Decoding Mammalian Ribosome-mRNA States by Translational GTPase ComplexesMycolactone subverts immunity by selectively blocking the Sec61 translocon.An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate.Low expression level of OB-Rb results from constitutive translocational attenuation attributable to a less efficient signal sequence.Structural basis for stop codon recognition in eukaryotes.A functional link between the co-translational protein translocation pathway and the UPR.Structures of the scanning and engaged states of the mammalian SRP-ribosome complex.Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation.Mechanistic basis for a molecular triage reactionThe ER membrane protein complex is a transmembrane domain insertase.UBE2O is a quality control factor for orphans of multiprotein complexes.ZNF598 Is a Quality Control Sensor of Collided RibosomesProteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature
P2860
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P2860
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@ast
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@en
type
label
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@ast
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@en
prefLabel
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@ast
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@en
P2093
P2860
P1476
In vitro dissection of protein translocation into the mammalian endoplasmic reticulum.
@en
P2093
Ajay Sharma
Malaiyalam Mariappan
Suhila Appathurai
P2860
P304
P356
10.1007/978-1-60327-412-8_20
P407
P577
2010-01-01T00:00:00Z