Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo. - Wikidata - wikimedia - TriplyDB

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

http://www.wikidata.org/entity/Q35067240

about

Zebrafish: a vertebrate tool for studying basal body biogenesis, structure, and function Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.Developmental disruptions underlying brain abnormalities in ciliopathies.A shift in anterior-posterior positional information underlies the fin-to-limb evolution.Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation.An essential role for Grk2 in Hedgehog signalling downstream of Smoothened.Transcriptional regulation of graded Hedgehog signaling Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.GLI3-related polydactyly: a review.Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms.Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling.Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7.Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo.Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules Sufu and Kif7 in limb patterning and development.Novel KIF7 missense substitutions in two patients presenting with multiple malformations and features of acrocallosal syndrome.Role and inhibition of GLI1 protein in cancer.

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Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

http://www.wikidata.org/entity/Q35067240

description

2013 nî lūn-bûn

@nan

2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

name

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@ast

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@en

type

label

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@ast

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@en

prefLabel

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@ast

Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@en

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JOURNAL.PGEN.1003955

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Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.

@en

P2093

Ashish Kumar Maurya

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Ashley Shu Mei Ng

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Audrey Iyu

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Fredericus J M van Eeden

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Jin Ben

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Raymond Teck Ho Lee

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Stone Elworthy

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Weimiao Yu

http://www.w3.org/2001/XMLSchema#string

Weixin Niah

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Zhonghua Zhao

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P2860

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

The zebrafish mutants dre, uki, and lep encode negative regulators of the hedgehog signaling pathway.

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

The Hedgehog and Wnt signalling pathways in cancer

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e1003955

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scholarly article

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10.1371/JOURNAL.PGEN.1003955

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Philip W Ingham

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2013-12-05T00:00:00Z

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259337319

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3854788

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