Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma - Wikidata - wikimedia - TriplyDB

Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma

Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma

http://www.wikidata.org/entity/Q35067627

about

Anti-Tumor Immunity in Head and Neck Cancer: Understanding the Evidence, How Tumors Escape and Immunotherapeutic Approaches Myeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor Microenvironment Targeting Immune Regulatory Networks to Counteract Immune Suppression in Cancer Improving cancer immunotherapy by targeting the STATe of MDSCs Neutrophils and Granulocytic MDSC: The Janus God of Cancer Immunotherapy Adjunct Strategies for Tuberculosis Vaccines: Modulating Key Immune Cell Regulatory Mechanisms to Potentiate Vaccination The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected Big opportunities for small molecules in immuno-oncology.Systemic inflammation is an independent predictive marker of clinical outcomes in mucosal squamous cell carcinoma of the head and neck in oropharyngeal and non-oropharyngeal patients.Nanoparticle delivery of CDDO-Me remodels the tumor microenvironment and enhances vaccine therapy for melanoma.The nitric oxide radical scavenger carboxy-PTIO reduces the immunosuppressive activity of myeloid-derived suppressor cells and potentiates the antitumor activity of adoptive cytotoxic T lymphocyte immunotherapy.The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma PD-1 blockade attenuates immunosuppressive myeloid cells due to inhibition of CD47/SIRPα axis in HPV negative head and neck squamous cell carcinoma.Enhancement of adoptive T cell transfer with single low dose pretreatment of doxorubicin or paclitaxel in mice.Overcoming barriers to effective immunotherapy: MDSCs, TAMs, and Tregs as mediators of the immunosuppressive microenvironment in head and neck cancer.CTLA4 blockade reduces immature myeloid cells in head and neck squamous cell carcinoma.Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.Indomethacin Treatment of Mice with Premalignant Oral Lesions Sustains Cytokine Production and Slows Progression to Cancer.Premalignant Oral Lesion Cells Elicit Increased Cytokine Production and Activation of T-cells.Molecular biology and immunology of head and neck cancer.The immunobiology of myeloid-derived suppressor cells in cancer.Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma.Regulatory T cells in oral squamous cell carcinoma.A clinical and biological perspective of human myeloid-derived suppressor cells in cancer.Myeloid-derived suppressor cells as effectors of immune suppression in cancer.Targeting cancer-related inflammation in the era of immunotherapy.Cancer-Related Systemic Inflammation: The Challenges and Therapeutic Opportunities for Personalized Medicine.Myeloid-Derived Suppressor Cells.Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption.Tadalafil has biologic activity in human melanoma. Results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe)T-cell immunoglobulin mucin 3 blockade drives an antitumor immune response in head and neck cancer.CD24 blunts oral squamous cancer development and dampens the functional expansion of myeloid-derived suppressor cells.LAG-3 confers poor prognosis and its blockade reshapes antitumor response in head and neck squamous cell carcinoma.Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening.Immunotherapy of cancer: targeting cancer during active disease or during dormancy?4PD Functionalized Dendrimers: A Flexible Tool for In Vivo Gene Silencing of Tumor-Educated Myeloid Cells.Use of phosphodiesterase type 5 inhibitors and risk of melanoma: a meta-analysis of observational studies.Avoiding phagocytosis-related artifact in myeloid derived suppressor cell T-lymphocyte suppression assays.CD45RA-Foxp3high regulatory T cells have a negative impact on the clinical outcome of head and neck squamous cell carcinoma.

P2860

Q26774312-8A7C4500-7785-487B-817C-E44B5DA06F56 Q26799126-B15BF59E-5DCD-4682-92F9-1241DFFC36F5 Q28066486-18FA8EFB-0896-408D-B9DC-5725FD6F3070 Q28066797-E423E93C-2A9E-410B-BF3E-1B44E91877AA Q28069360-D906E2A2-5349-48AA-B1B3-526A0C57E174 Q28074536-21F318A1-2952-4E50-8FEF-771738C867C0 Q28076760-433A810C-58B9-4DB5-9699-A8925CF036B3 Q28084627-258E577C-21ED-4865-8CC1-A6B024C1CA84 Q34487689-2C962B11-9E4F-4C96-B77C-874D703F5069 Q35927872-8F889CAD-A40B-496D-9073-37C52ABBF462 Q35999941-71B64451-1137-435D-867F-F4D8900BCBE7 Q36060268-10A67136-3A4D-4A05-9740-47A69B47D73C Q36458158-A5314464-6B9A-47A2-B74D-7D347AD68EEE Q36561681-D05B047C-7CDD-4E9D-B690-11E8E47BE05E Q36688932-0A1C5F5E-77C3-4E67-B7EB-C5F619DA96B4 Q37017190-B2DDF535-764D-4392-863A-07D3F6ECB050 Q37079094-AE8A446B-836D-4761-8564-369276281130 Q37079141-225D4A8A-5A69-4CEB-A2E3-F5D656581BA2 Q37273566-10D7243D-A38B-4B3E-B036-4F434E7F6D03 Q37274307-B456DAAF-ABC6-45B1-A5DA-0E0056171B7D Q38483321-35FC53CC-AFC4-4DFA-B395-5694B67B888B Q38649547-1C243A19-2785-4F7B-9F89-BD68813F1840 Q38731474-FB60C988-9E92-4C3C-BF5D-5792E6BE3080 Q38809637-6541297F-C0CB-4E4F-A496-FB129F18E5B8 Q38847251-6108104A-D702-49FF-99B5-41C6E170A8FC Q38864758-05B37C7D-D959-47B0-A3FE-D71444F566FA Q39044981-FABE9B22-F383-4CEF-A884-A721783DD629 Q39429983-96C3EC6D-5D2F-4D96-9700-61EBF58D918E Q40385399-DE7DB508-BD4A-4D00-AA0D-1E4C773FF93A Q40409853-9C461582-D05F-4FC7-8B1B-8081662679E8 Q41067892-79327DE3-A6C1-4B92-B376-20762B95B45F Q41127889-53BBDAA5-0B75-464E-A5AE-E9DE980589B4 Q41625073-B11EA0C7-2A73-4744-B77B-290C51A257C4 Q41997200-3BA99209-C5AC-4283-B4C6-35C22309E0FE Q45160017-29AFBE7D-5885-4CE3-AA7E-80B47CE1F09C Q47729557-4021A3A9-D82A-4237-BAC2-E51781C38184 Q48295124-61DA15BE-9B65-4CE1-A9A9-7F04230D8087 Q49298466-A42EB61F-F406-4BEF-865D-34D49112670A Q49644139-3FE077A3-C973-45B4-8DD4-457B95D73D54 Q50975027-05D2A2E2-EA47-4D0C-926F-6FA9250DA9EC

P2860

Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma

http://www.wikidata.org/entity/Q35067627

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@ast

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@en

type

label

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@ast

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@en

prefLabel

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@ast

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@en

P1433

Q35067627-C164192C-F606-44FC-85B4-F193638E2A35

P1476

Q35067627-4DDF0660-DEF9-42B1-AD97-9FFBF080B7DC

P2093

Q35067627-011C294A-96F8-4764-9AD9-3A20C0A43E47

Q35067627-1626D588-7E4D-472E-8E26-591633964F98

Q35067627-21B0EF69-5E2D-42AE-BF8E-13E0D1B5F728

Q35067627-68A31710-F096-46A6-9371-2DC4B9B288FF

Q35067627-74B2EF00-0160-4137-A8A5-7E9523EDB002

Q35067627-80A5E53D-530A-4FEC-B011-FB653993E52F

Q35067627-A2880FE7-05A8-4304-8035-D5026975D4D1

Q35067627-B10540E9-127A-4C9C-A614-36188291894E

Q35067627-BC77FE1E-307F-4043-A0FB-782A45CA4D54

Q35067627-D096B88B-4369-47C6-96F4-3928BBA1C4A3

P2860

Q35067627-011D8A71-340F-418E-B4BE-84A88C51F445

Q35067627-011FC083-D0B0-4B1B-84D2-19577308E2F8

Q35067627-01F57C4E-985D-42C2-BC79-2174ED5A11BB

Q35067627-107C8763-1B64-44D8-803A-86A4A5329B47

Q35067627-13FCB95E-EFD2-49F7-B63B-176B1D2385B2

Q35067627-17F1C7C3-6199-431A-B159-6CF34E59BDCB

Q35067627-1A3A8F0B-439F-4F46-8091-0A7D121F1278

Q35067627-3BFAA4CE-EEB0-4AC6-AF61-1B3BD9B44444

Q35067627-4288F0BE-1E34-4681-B6E1-7847B9FAF8DE

Q35067627-4A9FE600-AF61-42DD-A6AD-D95BACA2F3F2

P304

Q35067627-37BCDCED-A52F-4062-967A-0CB71341D572

P31

Q35067627-269B48ED-9B8C-41D6-A2E8-54D1D7CBC784

P356

Q35067627-DE1090EE-4F91-4193-8920-3A9B7FD64BCC

P407

Q35067627-6A3C213D-F32A-477B-8774-EF186C75200F

P433

Q35067627-FC1C37AB-CB9A-4051-AC40-1054719A75BF

P478

Q35067627-4E9C09C5-688B-48F3-BA68-41239696B046

P577

Q35067627-E5201AD7-06F7-4A7F-98C6-95FA41086743

P698

Q35067627-ADA9B414-18D0-4131-A1AB-73174FB3588C

P932

Q35067627-886ED169-92BA-427A-A6F0-7BE53065E3F3

P356

1078-0432.CCR-14-1711

P1433

Clinical Cancer Research

P1476

Tadalafil reduces myeloid-deri ...... d neck squamous cell carcinoma

@en

P2093

Adriana C De la Fuente

http://www.w3.org/2001/XMLSchema#string

Carmen Gomez

http://www.w3.org/2001/XMLSchema#string

Donald T Weed

http://www.w3.org/2001/XMLSchema#string

Isildinha M Reis

http://www.w3.org/2001/XMLSchema#string

Ivan Borrello

http://www.w3.org/2001/XMLSchema#string

Jennifer L Vella

http://www.w3.org/2001/XMLSchema#string

Joseph Califano

http://www.w3.org/2001/XMLSchema#string

Paolo Serafini

http://www.w3.org/2001/XMLSchema#string

Ronen Nazarian

http://www.w3.org/2001/XMLSchema#string

Zoukaa Sargi

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanisms of immune suppression in patients with head and neck cancer: presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocyte-macrophage colony-stimulating factor

Subcellular localization of FOXP3 in human regulatory and nonregulatory T cells

Expression of PDE11A in normal and malignant human tissues

Potency, selectivity, and consequences of nonselectivity of PDE inhibition

High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells.

Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular disease.

FOXP3 subcellular localization predicts recurrence in oral squamous cell carcinoma.

P304

39-48

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/1078-0432.CCR-14-1711

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P577

2014-10-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

25320361

http://www.w3.org/2001/XMLSchema#string

P932

4322895

http://www.w3.org/2001/XMLSchema#string