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Airway smooth muscle as a target of asthma therapy: history and new directions.

Airway smooth muscle as a target of asthma therapy: history and new directions.

http://www.wikidata.org/entity/Q35070197

about

TRP Channels in Respiratory Pathophysiology: the Role of Oxidative, Chemical Irritant and Temperature Stimuli Antagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium.Treatment of experimental asthma using a single small molecule with anti-inflammatory and BK channel-activating properties.Effect of aging on cellular mechanotransduction Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations.Effect of tumor suppressor PTEN gene on apoptosis and cell cycle of human airway smooth muscle cells.Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models.Tissue factor pathway inhibitor attenuates the progression of malignant pleural mesothelioma in nude mice.Intestinal, airway, and cardiovascular relaxant activities of thymoquinone S100A8/A9: a mediator of severe asthma pathogenesis and morbidity?H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal K(ATP) channel.Ion channels in asthma.Revisiting the usefulness of thromboxane-A2 modulation in the treatment of bronchoconstriction in asthma.IL-1β: a key modulator in asthmatic airway smooth muscle hyper-reactivity.Asthma and early herniated intervertebral disc disease.Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB.Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor.Regulation of airway contractility by plasminogen activators through N-methyl-D-aspartate receptor-1.Cardiovascular and airway relaxant activities of peony root extract.Chloroform Extract of Artemisia annua L. Relaxes Mouse Airway Smooth Muscle.Microfluidic chest cavities reveal that transmural pressure controls the rate of lung development.Role of endothelin-1 for the regulation of renal pelvic function.

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P2860

Airway smooth muscle as a target of asthma therapy: history and new directions.

http://www.wikidata.org/entity/Q35070197

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2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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Airway smooth muscle as a target of asthma therapy: history and new directions.

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Airway smooth muscle as a target of asthma therapy: history and new directions.

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Airway smooth muscle as a target of asthma therapy: history and new directions.

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Airway smooth muscle as a target of asthma therapy: history and new directions.

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Respiratory Research

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Airway smooth muscle as a target of asthma therapy: history and new directions.

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Kieran Killian

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Luke J Janssen

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Creative Commons Attribution 2.0 Generic

P2860

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility

Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs

Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats

Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle

Invited review: cross-bridge regulation by thin filament-associated proteins

A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea

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