A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice. - Wikidata - wikimedia - TriplyDB

A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice.

A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice.

http://www.wikidata.org/entity/Q35071632

about

Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity MIF: Implications in the Pathoetiology of Systemic Lupus Erythematosus Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the β-sheet structure of MIF.Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor.Macrophage migration inhibitory factor is involved in ectopic endometrial tissue growth and peritoneal-endometrial tissue interaction in vivo: a plausible link to endometriosis development.MIF, a controversial cytokine: a review of structural features, challenges, and opportunities for drug development.Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA.Macrophage migration inhibitory factor: a multifunctional cytokine in rheumatic diseases.Endothelial CD74 mediates macrophage migration inhibitory factor protection in hyperoxic lung injury Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus.Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.Beneficial effect of Bupleurum polysaccharides on autoimmune-prone MRL-lpr mice.New insights into the role and mechanism of macrophage migration inhibitory factor in steroid-resistant patients with systemic lupus erythematosus.Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-γ.Macrophage migration inhibitory factor produced by the tumour stroma but not by tumour cells regulates angiogenesis in the B16-F10 melanoma model.Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus.Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74 Cytokines in sepsis: potent immunoregulators and potential therapeutic targets--an updated view.Spirohexenolide A targets human macrophage migration inhibitory factor (hMIF)Association of MIF, but not type I interferon-induced chemokines, with increased disease activity in Asian patients with systemic lupus erythematosus.Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction.Association of macrophage migration inhibitory factor promoter polymorphism -173G/C with susceptibility to childhood asthma.MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis.Beta cell function: the role of macrophage migration inhibitory factor.D-dopachrome tautomerase (D-DT or MIF-2): doubling the MIF cytokine family.MIF, MIF alleles, and prospects for therapeutic intervention in autoimmunity.Brain miffed by macrophage migration inhibitory factor.Macrophage Migration Inhibitory Factor Limits Renal Inflammation and Fibrosis by Counteracting Tubular Cell Cycle Arrest.The non-mammalian MIF superfamily.MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics.Re-Examining Neutrophil Participation in GN.Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus.Modulating of ocular inflammation with macrophage migration inhibitory factor is associated with notch signalling in experimental autoimmune uveitis.Ribosomal protein S19 is a novel therapeutic agent in inflammatory kidney disease.MIF Inhibitor ISO-1 Protects Photoreceptors and Reduces Gliosis in Experimental Retinal Detachment.Cytokine MIF Enhances Blood-Brain Barrier Permeability: Impact for Therapy in Ischemic Stroke.CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice.The relevance of the migration inhibitory factor (MIF) for peripheral tissue response in murine sublethal systemic Aspergillus fumigatus infection.Reduced Osteoarthritis Severity in Aged Mice With Deletion of Macrophage Migration Inhibitory Factor.

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A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice.

http://www.wikidata.org/entity/Q35071632

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

A small-molecule macrophage mi ...... e NZB/NZW F1 and MRL/lpr mice.

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A small-molecule macrophage mi ...... e NZB/NZW F1 and MRL/lpr mice.

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A small-molecule macrophage mi ...... e NZB/NZW F1 and MRL/lpr mice.

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A small-molecule macrophage mi ...... e NZB/NZW F1 and MRL/lpr mice.

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A small-molecule macrophage mi ...... e NZB/NZW F1 and MRL/lpr mice.

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A small-molecule macrophage mi ...... e NZB/NZW F1 and MRL/lpr mice.

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JIMMUNOL.1001767

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Journal of Immunology

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A small-molecule macrophage mi ...... ne NZB/NZW F1 and MRL/lpr mice

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P2093

Alvaro Arjona

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David Austin

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Dorothee Greven

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Juan Fan

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Liang Chen

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Lin Leng

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Michael Kashgarian

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Richard Bucala

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Xiao R Huang

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Xin Du

http://www.w3.org/2001/XMLSchema#string

P2860

A proinflammatory cytokine inhibits p53 tumor suppressor activity

MIF signal transduction initiated by binding to CD74

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex

A functional heteromeric MIF receptor formed by CD74 and CXCR4

The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction

Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion

Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity

The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents

Crystal structure of the macrophage migration inhibitory factor from rat liver

Macrophage migration inhibitory factor: a regulator of innate immunity

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527-538

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scholarly article

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10.4049/JIMMUNOL.1001767

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1

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186

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David J Nikolic-Paterson

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2010-11-24T00:00:00Z

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49635078

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21106847

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glomerulonephritis

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3124407

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