An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.

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http://www.wikidata.org/entity/Q35077677

Q35077677

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Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1 Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cells ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2 HIV Epidemic in Asia: Implications for HIV Vaccine and Other Prevention Trials.A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies Immune-correlates analysis of an HIV-1 vaccine efficacy trial Survivors Remorse: antibody-mediated protection against HIV-1.Soluble Envelope Glycoprotein Trimers from a CD4-Independent HIV-1 Elicit Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Guinea Pigs Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design.HIV prevention transformed: the new prevention research agenda Identification of dominant antibody-dependent cell-mediated cytotoxicity epitopes on the hemagglutinin antigen of pandemic H1N1 influenza virus.Lessons learned from human HIV vaccine trials.HIV-1 vaccines: challenges and new perspectives Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection Novel directions in HIV-1 vaccines revealed from clinical trials Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates.Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities.Epitope target structures of Fc-mediated effector function during HIV-1 acquisition.Nonneutralizing functional antibodies: a new "old" paradigm for HIV vaccines Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial.HIV Nef and Vpu protect HIV-infected CD4+ T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2.Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.Isolate-specific differences in the conformational dynamics and antigenicity of HIV-1 gp120.The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals Slaying the Trojan horse: natural killer cells exhibit robust anti-HIV-1 antibody-dependent activation and cytolysis against allogeneic T cells Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection.Activation of NK cells by ADCC antibodies and HIV disease progression.Conserved molecular signatures in gp120 are associated with the genetic bottleneck during simian immunodeficiency virus (SIV), SIV-human immunodeficiency virus (SHIV), and HIV type 1 (HIV-1) transmission Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function.What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure?Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

P2860

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P2860

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.

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http://www.wikidata.org/entity/Q35077677

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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