Altered hippocampal synaptic physiology in aged parkin-deficient mice. - Wikidata - wikimedia - TriplyDB

Altered hippocampal synaptic physiology in aged parkin-deficient mice.

Altered hippocampal synaptic physiology in aged parkin-deficient mice.

http://www.wikidata.org/entity/Q35078309

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Imbalanced pattern completion vs. separation in cognitive disease: network simulations of synaptic pathologies predict a personalized therapeutics strategy.Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis.Parkin Deficiency Reduces Hippocampal Glutamatergic Neurotransmission by Impairing AMPA Receptor Endocytosis.Synaptic dysfunction in genetic models of Parkinson's disease: a role for autophagy?Forebrain depletion of Rheb GTPase elicits spatial memory deficits in mice.Autophagy in synaptic development, function, and pathology.Mouse models of neurodegenerative disease: preclinical imaging and neurovascular component.Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice.Parkinson's disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons

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Altered hippocampal synaptic physiology in aged parkin-deficient mice.

http://www.wikidata.org/entity/Q35078309

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Altered hippocampal synaptic physiology in aged parkin-deficient mice.

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Altered hippocampal synaptic physiology in aged parkin-deficient mice.

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type

label

Altered hippocampal synaptic physiology in aged parkin-deficient mice.

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Altered hippocampal synaptic physiology in aged parkin-deficient mice.

@en

prefLabel

Altered hippocampal synaptic physiology in aged parkin-deficient mice.

@ast

Altered hippocampal synaptic physiology in aged parkin-deficient mice.

@en

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NeuroMolecular Medicine

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Altered hippocampal synaptic physiology in aged parkin-deficient mice.

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Adrienne L Orr

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Daniel V Madison

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Jesse E Hanson

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P2860

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI

Parkin-deficient mice are not a robust model of parkinsonism.

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain

Pruning and loss of excitatory synapses by the parkin ubiquitin ligase

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3

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