Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.
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Dietary flavonoid fisetin: a novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer managementA Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in micePterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor statusAdditive Effect of Zfhx3/Atbf1 and Pten Deletion on Mouse Prostatic TumorigenesisDeletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways.Transcriptional activity of c-Jun is critical for the suppression of AR function.The current state of preclinical prostate cancer animal models.BRAF activation initiates but does not maintain invasive prostate adenocarcinomaAnalysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems.Endothelial cell-derived interleukin-6 regulates tumor growth.Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing.TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.The tumor suppressive role of CAMK2N1 in castration-resistant prostate cancer.Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptorMolecular genetics of prostate cancer: new prospects for old challengesSPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene.Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.Molecular pathways and targets in prostate cancerSprouty genes function in suppression of prostate tumorigenesisConditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling.Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice.CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling.Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis.Conditional expression of the androgen receptor induces oncogenic transformation of the mouse prostate.BRAF Mutations in Canine Cancers.Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer.Combined AKT and MEK Pathway Blockade in Pre-Clinical Models of Enzalutamide-Resistant Prostate Cancer.Activating BRAF gene mutations are uncommon in hormone refractory prostate cancer in Caucasian patientsB-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancerAndrogen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice.Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse modelModulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implicationsTargeting the androgen receptor pathway in prostate cancer.AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion.Portrait of PTEN: messages from mutant mice.The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanismsEffects of manganese superoxide dismutase silencing on androgen receptor function and gene regulation: implications for castration-resistant prostate cancer
P2860
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P2860
Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Combinatorial activities of Ak ...... n-independent prostate cancer.
@ast
Combinatorial activities of Ak ...... n-independent prostate cancer.
@en
type
label
Combinatorial activities of Ak ...... n-independent prostate cancer.
@ast
Combinatorial activities of Ak ...... n-independent prostate cancer.
@en
prefLabel
Combinatorial activities of Ak ...... n-independent prostate cancer.
@ast
Combinatorial activities of Ak ...... n-independent prostate cancer.
@en
P2093
P2860
P356
P1476
Combinatorial activities of Ak ...... n-independent prostate cancer.
@en
P2093
Cory Abate-Shen
Michael M Shen
Whitney A Banach-Petrosky
William L Gerald
Xuesong Ouyang
P2860
P304
14477-14482
P356
10.1073/PNAS.0606836103
P407
P577
2006-09-14T00:00:00Z