Mantle cell lymphoma is characterized by inactivation of the ATM gene.
about
Constitutive activation of the Wnt canonical pathway in mantle cell lymphomaMolecular pathology of ataxia telangiectasiaSapacitabine for cancerTherapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors.Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agentsLoss of p53 Ser18 and Atm results in embryonic lethality without cooperation in tumorigenesisGenetic features of B-cell chronic lymphocytic leukemia.Detecting statistical interaction between somatic mutational events and germline variation from next-generation sequence data.Computational refinement of functional single nucleotide polymorphisms associated with ATM geneHuman MRE11 is inactivated in mismatch repair-deficient cancers.Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma.BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like.Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling.Metastasis of neuroendocrine tumors are characterized by increased cell proliferation and reduced expression of the ATM geneTargeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm.Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells.ATM gene and lymphoid malignancies.Ataxia telangiectasia gene mutations in leukaemia and lymphoma.Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes.Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma.Mantle cell lymphoma: a biological and therapeutic paradigm.Cytogenetic analysis in mantle cell lymphoma: a review of 214 cases.ATM mutations in sporadic lymphoid tumours.Oligonucleotide microarrays demonstrate the highest frequency of ATM mutations in the mantle cell subtype of lymphomaPeripheral blood complete remission after splenic irradiation in mantle-cell lymphoma with 11q22-23 deletion and ATM inactivation.Molecular basis of mantle cell lymphoma.Development of a murine model for blastoid variant mantle-cell lymphomaMechanisms of B-cell lymphoma pathogenesis.Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans.Loss of chromosome 11q21-23.1 and 17p and gain of chromosome 6p are independent prognostic indicators in B-cell non-Hodgkin's lymphoma.Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature.Molecular variants of the ATM gene in Hodgkin's disease in children.Predicting the outcome in non-Hodgkin lymphoma with molecular markers.Male-to-female sex ratios of abnormalities detected by fluorescence in situ hybridization in a population of chronic lymphocytic leukemia patients.ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors.Poly(ADP-ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic.Abnormalities of DNA repair mechanisms in common hematological malignancies.Predictive biomarkers for cancer therapy with PARP inhibitors.
P2860
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P2860
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
description
2000 nî lūn-bûn
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2000年の論文
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Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@ast
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@en
type
label
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@ast
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@en
prefLabel
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@ast
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@en
P2093
P2860
P356
P1476
Mantle cell lymphoma is characterized by inactivation of the ATM gene.
@en
P2093
Schaffner C
Stilgenbauer S
P2860
P304
P356
10.1073/PNAS.050400997
P407
P577
2000-03-01T00:00:00Z