p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia. - Wikidata - wikimedia - TriplyDB

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

http://www.wikidata.org/entity/Q35083267

about

Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2)The unusual mechanism of inhibition of the p90 ribosomal S6 kinase (RSK) by flavonol rhamnosides.Luteolin, a novel p90 ribosomal S6 kinase inhibitor, suppresses proliferation and migration in leukemia cells Regulation of the kinase RSK1 by arsenic trioxide and generation of antileukemic responses The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis While at Rome miRNA and TRAIL do whatever BCR-ABL commands to do.Ribosomal S6 kinase (RSK) modulators: a patent review.The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

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p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

http://www.wikidata.org/entity/Q35083267

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

@ast

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

@en

type

label

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

@ast

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

@en

prefLabel

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

@ast

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

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p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia

@en

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Benjamin H Lee

http://www.w3.org/2001/XMLSchema#string

Dean Blevins

http://www.w3.org/2001/XMLSchema#string

Hanna J Khoury

http://www.w3.org/2001/XMLSchema#string

Jack Taunton

http://www.w3.org/2001/XMLSchema#string

Jian-Xin Lin

http://www.w3.org/2001/XMLSchema#string

Lingtao Jin

http://www.w3.org/2001/XMLSchema#string

Shannon Elf

http://www.w3.org/2001/XMLSchema#string

Sumin Kang

http://www.w3.org/2001/XMLSchema#string

Tae-Wook Chung

http://www.w3.org/2001/XMLSchema#string

Warren J Leonard

http://www.w3.org/2001/XMLSchema#string

P2860

Rsk1 mediates a MEK-MAP kinase cell survival signal

C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival

The RSK family of kinases: emerging roles in cellular signalling

Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome

Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

The serine/threonine protein kinase, p90 ribosomal S6 kinase, is an important regulator of prostate cancer cell proliferation.

RSK2 mediates muscle cell differentiation through regulation of NFAT3.

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases.

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6885-6894

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10.1182/BLOOD-2010-10-315721

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21527514

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