The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells - Wikidata - wikimedia - TriplyDB

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells

http://www.wikidata.org/entity/Q35083432

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SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress Mitochondrial Quality Control and Muscle Mass Maintenance Glucose stimulation induces dynamic change of mitochondrial morphology to promote insulin secretion in the insulinoma cell line INS-1E Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage Mitochondrial division and fusion in metabolism Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity.Multiplex micro-respiratory measurements of Arabidopsis tissues.Role of Mitochondria in Alcoholic Liver Disease A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver.Mitochondrial morphological features are associated with fission and fusion events Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage.Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells.Diabetes reduces β-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology.Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity.p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival.Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development.Rhein protects pancreatic β-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes.Mitochondrial dynamics in neurodegeneration.Mitochondrial dynamics and morphology in beta-cells.Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure.New roles for OMA1 metalloprotease: From mitochondrial proteostasis to metabolic homeostasis.Mitochondrial dynamic changes in health and genetic diseases.Mitochondrial dynamics, mitophagy and cardiovascular disease.Mitochondrial network regulation and its potential interference with inflammatory signals in pancreatic beta cells.Role of Mitochondrial Dysfunction in Hypertension and Obesity.Mitochondrial morphology and dynamics in hepatocytes from normal and ethanol-fed rats.Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.Chronic Exposure to Proline Causes Aminoacidotoxicity and Impaired Beta-Cell Function: Studies In Vitro.Mitochondrial dynamics: functional link with apoptosis.Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency.IL-1β hampers glucose-stimulated insulin secretion in Cohen diabetic rat islets through mitochondrial cytochrome c oxidase inhibition by nitric oxide.The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure.OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.The emerging role of immune dysfunction in mitochondrial diseases as a paradigm for understanding immunometabolism.

P2860

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P2860

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells

http://www.wikidata.org/entity/Q35083432

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

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The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

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type

label

The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

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The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

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prefLabel

The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

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The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

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P1433

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P2860

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MBC.E10-12-0933

P1433

Molecular Biology of the Cell

P1476

The dynamin-related GTPase Opa ...... ction in pancreatic beta cells

@en

P2093

Brian M Polster

http://www.w3.org/2001/XMLSchema#string

Hiromi Sesaki

http://www.w3.org/2001/XMLSchema#string

Junko Wakabayashi

http://www.w3.org/2001/XMLSchema#string

Mehboob A Hussain

http://www.w3.org/2001/XMLSchema#string

Miho Iijima

http://www.w3.org/2001/XMLSchema#string

Mikhail V Pletnikov

http://www.w3.org/2001/XMLSchema#string

Nobunao Wakabayashi

http://www.w3.org/2001/XMLSchema#string

Orian S Shirihai

http://www.w3.org/2001/XMLSchema#string

Pascaline Clerc

http://www.w3.org/2001/XMLSchema#string

Sam Sereda

http://www.w3.org/2001/XMLSchema#string

P2860

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

OPA1 requires mitofusin 1 to promote mitochondrial fusion

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals

Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria.

Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1.

Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.

Mitochondria: dynamic organelles in disease, aging, and development

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

P304

2235-2245

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P31

scholarly article

P356

10.1091/MBC.E10-12-0933

http://www.w3.org/2001/XMLSchema#string

P433

13

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P478

22

http://www.w3.org/2001/XMLSchema#string

P577

2011-05-05T00:00:00Z

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21551073

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P932

3128526

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