Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin

Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin

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http://www.wikidata.org/entity/Q35083478

Q35083478

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N-glycans of core2 beta(1,6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of alpha(1,3)-fucosyltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): effects on P-, L- and E-se Knockdown of fucosyltransferase III disrupts the adhesion of circulating cancer cells to E-selectin without affecting hematopoietic cell adhesion Cytolethal distending toxin family members are differentially affected by alterations in host glycans and membrane cholesterol.Fucosylation in prokaryotes and eukaryotes.Gene expression in rats with Barrett's esophagus and esophageal adenocarcinoma induced by gastroduodenoesophageal reflux.Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis.The selectin-selectin ligand axis in tumor progression.Inhibitor of apoptosis protein expression in glioblastomas and their in vitro and in vivo targeting by SMAC mimetic GDC-0152 Systemic inflammation increases cancer cell adhesion to hepatic sinusoids by neutrophil mediated mechanisms.Effects of cell surface α2-3 sialic acid on osteogenesis.E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release.Alpha1,2fucosylation is a superior predictor of postoperative prognosis for colorectal cancer compared with blood group A, B, or sialyl Lewis X antigen generated within colorectal tumor tissues.FUT1 genetic variants impact protein glycosylation of porcine intestinal mucosa.Recognition of blood group ABH type 1 determinants by the FedF adhesin of F18-fimbriated Escherichia coli.Directing flux in glycan biosynthetic pathways with a small molecule switch.Transcriptional regulation of fucosyltransferase 1 gene expression in colon cancer cells.Introducing alpha(1,2)-linked fucose into hepatocarcinoma cells inhibits vasculogenesis and tumor growth.Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF-β induced EMT in pancreatic cancer cells.

P2860

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P2860

Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin

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http://www.wikidata.org/entity/Q35083478

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2004 nî lūn-bûn

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2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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