Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR. - Wikidata - wikimedia - TriplyDB

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

http://www.wikidata.org/entity/Q35083635

about

The nerve of ovulation-inducing factor in semen Neurotrophin-regulated signalling pathways The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders A DR6/p75(NTR) complex is responsible for β-amyloid-induced cortical neuron death Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction Age-dependent alterations in nerve growth factor (NGF)-related proteins, sortilin, and learning and memory in rats Propofol anesthesia induces proapoptotic tumor necrosis factor-α and pro-nerve growth factor signaling and prosurvival Akt and XIAP expression in neonatal rat brain.Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling.Identification of a linear epitope in sortilin that partakes in pro-neurotrophin binding.Small molecule activators of the Trk receptors for neuroprotection Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling.Understanding proneurotrophin actions: Recent advances and challenges.Sortilin participates in light-dependent photoreceptor degeneration in vivo.ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons The yin and yang of neurotrophin action.Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats.Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis.Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.Regulation of NGF and NT-3 protein expression in peripheral targets by sympathetic input Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation Pro-NGF, sortilin, and p75NTR: potential mediators of injury-induced apoptosis in the mouse dorsal root ganglion.Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation Nerve growth factor, neural stem cells and Alzheimer's disease.p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer's disease Pro-NGF secreted by astrocytes promotes motor neuron cell death.Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures.Brain banks: benefits, limitations and cautions concerning the use of post-mortem brain tissue for molecular studies.Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors Astrocyte, the star avatar: redefined.Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.Nerve growth factor metabolic dysfunction in Down's syndrome brains.Effects of sustained proNGF blockade on attentional capacities in aged rats with compromised cholinergic system.Interleukin-1β enhances neuronal vulnerability to proNGF-mediated apoptosis by increasing surface expression of p75(NTR) and sortillin.Proneurotrophins, seizures, and neuronal apoptosis.MAGED1: molecular insights and clinical implications.The entorhinal cortex and neurotrophin signaling in Alzheimer's disease and other disorders.Dynamic nature of the p75 neurotrophin receptor in response to injury and disease

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P2860

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

http://www.wikidata.org/entity/Q35083635

description

2005 nî lūn-bûn

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2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2005 թվականի փետրվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

@ast

Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

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type

label

Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

@ast

Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

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prefLabel

Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

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Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

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S0002-9440(10)62275-4

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The American Journal of Pathology

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Pro-NGF isolated from the huma ...... apoptosis mediated by p75NTR.

@en

P2093

Barbara Hempstead

http://www.w3.org/2001/XMLSchema#string

Carlos E Pedraza

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Carme Espinet

http://www.w3.org/2001/XMLSchema#string

Isidre Ferrer

http://www.w3.org/2001/XMLSchema#string

Juan Carlos Arévalo

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Montse Iglesias

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Noemí Vidal

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Petar Podlesniy

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Ramee Lee

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P2860

Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

Regulation of cell survival by secreted proneurotrophins.

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

Translating cell biology into therapeutic advances in Alzheimer's disease.

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

Neurotrophins: to cleave or not to cleave.

The many faces of p75NTR.

Neurotrophin signaling through the p75 neurotrophin receptor.

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533-543

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10.1016/S0002-9440(10)62275-4

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2

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166

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2005-02-01T00:00:00Z

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8050132

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15681836

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Alzheimer's disease

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1602327

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