Signaling life and death in the thymus: timing is everything.
about
Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signalingModeling T cell antigen discrimination based on feedback control of digital ERK responsesUnderstanding the biosynthesis of platelets-derived extracellular vesiclesThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsCaspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasionStructural Model of the Extracellular Assembly of the TCR-CD3 Complex.Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte developmentContribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loadingComprehensive logic based analyses of Toll-like receptor 4 signal transduction pathwayLck SH3 domain function is required for T-cell receptor signals regulating thymocyte development.Sustained activation of extracellular signal-regulated kinase by nerve growth factor regulates c-fos protein stabilization and transactivation in PC12 cells.SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levelsRecombinatorial cloning using heterologous lox sites.The SCHOOL of nature: I. Transmembrane signaling.The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study.The protective role of 5-hydroxymethyl-2-furfural (5-HMF) against acute hypobaric hypoxiaTransforming Boolean models to continuous models: methodology and application to T-cell receptor signaling.Is thymocyte development functional in the aged?Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strainUnexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cellsThymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selectionShb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.The death effector domain protein PEA-15 negatively regulates T-cell receptor signaling.QUANTITATIVE MORPHOLOGICAL AND MOLECULAR PATHOLOGY OF THE HUMAN THYMUS CORRELATE WITH INFANT CAUSE OF DEATH.Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities.Mast cell survival and activation by IgE in the absence of antigen: a consideration of the biologic mechanisms and relevance.A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.A new function for LAT and CD8 during CD8-mediated apoptosis that is independent of TCR signal transductionA conformational change senses the strength of T cell receptor-ligand interaction during thymic selection.Signaling in thymic selection.Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activationPARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.Signaling from p53 to NF-kappa B determines the chemotherapy responsiveness of neuroblastoma.Surface T-cell antigen receptor expression and availability for long-term antigenic signaling.Age-dependent changes in the nervous and endocrine control of the thymus.An alternative to current thinking about positive selection, negative selection and activation of T cells.T cell receptor signaling that regulates the development of intrathymic natural regulatory T cells.Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: implications for autism.T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytesHematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.
P2860
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P2860
Signaling life and death in the thymus: timing is everything.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Signaling life and death in the thymus: timing is everything.
@ast
Signaling life and death in the thymus: timing is everything.
@en
type
label
Signaling life and death in the thymus: timing is everything.
@ast
Signaling life and death in the thymus: timing is everything.
@en
prefLabel
Signaling life and death in the thymus: timing is everything.
@ast
Signaling life and death in the thymus: timing is everything.
@en
P2093
P356
P1433
P1476
Signaling life and death in the thymus: timing is everything.
@en
P2093
Barbara Hausmann
Dieter Naeher
Guy Werlen
P304
P356
10.1126/SCIENCE.1067833
P407
P577
2003-03-01T00:00:00Z