The function of the protein tyrosine phosphatase SHP-1 in cancer.
about
Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migrationTetraspanin CD37 directly mediates transduction of survival and apoptotic signalsOverexpression of PIAS3 suppresses cell growth and restores the drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivationRedox balance dynamically regulates vascular growth and remodelingCrystal structure of human protein tyrosine phosphatase SHP-1 in the open conformationComprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation SequencingRole of protein tyrosine phosphatases in cancerSuppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injuryCpG sites associated with cigarette smoking: analysis of epigenome-wide data from the Sister StudyAn epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla.Analysis of SHP-1-mediated down-regulation of the TRK-T3 oncoprotein identifies Trk-fused gene (TFG) as a novel SHP-1-interacting protein.Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.5-hydroxy-2-methyl-1,4-naphthoquinone, a vitamin K3 analogue, suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase, SHP-1: potential role in chemosensitization.Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia.Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.SHP-1 and IL-1α conspire to provoke neutrophilic dermatoses.SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients.The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions.Chronic myeloid leukemia: mechanisms of blastic transformationDeep-sequencing analysis of the mouse transcriptome response to infection with Brucella melitensis strains of differing virulence.Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cellsMethylation profiling of SOCS1, SOCS2, SOCS3, CISH and SHP1 in Philadelphia-negative myeloproliferative neoplasmSHP-1 is a target of regorafenib in colorectal cancer.Significance of SHP-1 and SHP-2 expression in human papillomavirus infected Condyloma acuminatum and cervical cancer.SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinomaPTP1B suppresses prolactin activation of Stat5 in breast cancer cells.Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu miceDownregulation of signal transducer and activator of transcription 3 by sorafenib: a novel mechanism for hepatocellular carcinoma therapy.SHP-1 regulation of mast cell function in allergic inflammation and anaphylaxis.Erythroblast transformation by the friend spleen focus-forming virus is associated with a block in erythropoietin-induced STAT1 phosphorylation and DNA binding and correlates with high expression of the hematopoietic phosphatase SHP-1.Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia.The immunomodulating roles of glycoproteins in epithelial ovarian cancer.Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis.Regulation of hERG and hEAG channels by Src and by SHP-1 tyrosine phosphatase via an ITIM region in the cyclic nucleotide binding domainSMIP-016 in action: CD37 as a death receptorThe role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression.Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia.MHC class II transactivator (CIITA) expression is upregulated in multiple myeloma cells by IFN-gamma.
P2860
Q24315888-7C6834D0-28D2-4663-8DDC-8A498A816674Q24336378-17EDDFF9-6567-46C2-A866-31F001A2A0BDQ24678516-DE52D6B6-918F-4204-9B6E-952244742156Q27004547-DC6A661C-49FB-458B-AA74-9B4256FB9AD4Q27667430-434E09C6-C3DC-4487-9D49-E0C0BE9A0467Q28547976-978ED73A-2B36-43FA-A718-7546F851942DQ28741003-EA21CE74-75DE-4010-891A-BF319542A6BEQ30539371-5464F5FC-A1AE-4758-A959-15CB74A99A68Q30794295-9EEA2A47-7A43-40DF-AAAC-E2C9E1DF8A30Q31162257-9003BF6B-ACE6-4E09-ABCA-3D8525ECCB7BQ33292197-C63A5C46-B424-4536-97D2-B6564A1A3E80Q33350768-A2427003-493B-464C-B81D-E9A40A96D29EQ33598740-FE28051D-B5F2-4B63-8505-4079C15F24FBQ33687809-87259AB5-F8FA-4CBF-9BE7-DB9CE13764D8Q33838824-32B174A7-93FF-42C6-953D-C4C3951B49A4Q33854949-833B449B-6A96-4648-996A-01B11F88B892Q33879341-C6392E98-7255-4099-8D42-5702453B2325Q33879997-CEEE6EB4-750B-4F7C-AFD1-0EB5F6FFC7FFQ33904273-FFCF3B79-7A97-474F-850B-D5A7D6E58D5DQ33924261-D379BE18-E8D7-4D24-89E2-545D423146DBQ33968037-16251BD7-3514-4445-89F4-DEAEABA0974FQ34116929-D737EE1C-9BE5-41B3-9796-0CA2596053BFQ34133257-8C5FD9E3-D28E-4D6E-AA1D-A4D5546E42F5Q34154772-37EA767D-4EE1-45CA-A6A2-45A790BF93F6Q34227671-96B1ED7B-9BE9-43D9-A732-55E214039988Q34245628-66A0BF7D-0B3A-4F93-902B-1A78EE5C25ABQ34347235-C1C31C2D-EF65-4351-AD6F-B6B3BDD4925FQ34358316-B90CEC28-9A91-40CD-AA97-30C7415DEDE9Q34399334-A4E5AC60-587B-4E12-945A-EFF6D753F1C9Q34467228-CC1EE7EA-DB34-47C6-A5DA-99B9BB1C054CQ34580138-075BFB81-98D5-4074-A564-40CBF4407B76Q34651509-EDCA1D5F-FBF5-42C4-B6BE-EFE0E4F95E54Q34747359-422A6978-0A06-475A-A8DE-6DBB22F35E83Q35077893-61E8BF34-27C7-44F9-83A9-279A3B8A7DB3Q35091267-A882ED04-C87F-47D0-B275-AED1EB34C663Q35108594-24A16E6B-45E7-4EFF-997B-CD2100FC7BD6Q35186444-507AAF8F-B03F-4AD2-BDE7-7505299E72ECQ35688212-7C4D178D-5EB6-4F19-825A-B04321478B9CQ35835233-A65E4D0D-3F6E-4B14-BD46-190D612906F3Q35842817-A1FF8D24-7A5E-4732-BA00-418451A7673B
P2860
The function of the protein tyrosine phosphatase SHP-1 in cancer.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@ast
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@en
type
label
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@ast
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@en
prefLabel
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@ast
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@en
P2093
P1433
P1476
The function of the protein tyrosine phosphatase SHP-1 in cancer.
@en
P2093
Chengyu Wu
G Wayne Zhou
Mingzhong Sun
P356
10.1016/S0378-1119(03)00400-1
P407
P577
2003-03-01T00:00:00Z