PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation
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Wig1 prevents cellular senescence by regulating p21 mRNA decay through control of RISC recruitmentTherapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolveRestoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma.Silencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells.Exploiting tumor cell senescence in anticancer therapyDifferences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.Senescence and apoptosis: dueling or complementary cell fates?Aging-related gene signature regulated by Nlrp3 predicts glioma progression.Coordination between p21 and DDB2 in the cellular response to UV radiation.Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastropheGenomic aberrations in pediatric diffuse intrinsic pontine gliomasApoptosis and the target genes of microRNA-21.MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer.MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN.Lamin B1 loss is a senescence-associated biomarker.Autophagy and lysosomal related protein expression patterns in human glioblastoma.p63 the guardian of human reproduction.Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis.Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways.Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisationSenescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuliHeparan sulfation is essential for the prevention of cellular senescence.Combination of a STAT3 Inhibitor and an mTOR Inhibitor Against a Temozolomide-resistant Glioblastoma Cell Line.MEK1 is required for the development of NRAS-driven leukemia.Cellular Senescence - its role in cancer and the response to ionizing radiation.Interleukins in glioblastoma pathophysiology: implications for therapy.NRF2 and p53: Januses in cancer?Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway.Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.Cyclin A1 expression and paclitaxel resistance in human ovarian cancer cells.Treatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives.UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.HDAC inhibitor DWP0016 activates p53 transcription and acetylation to inhibit cell growth in U251 glioblastoma cells.Identification of NCF2/p67phox as a novel p53 target geneEffects of 837 and 1950 MHz radiofrequency radiation exposure alone or combined on oxidative stress in MCF10A cells.Cell Cycle Control by PTEN.Cell cycle arrest and apoptosis by expression of a novel TPIP (TPIP-C2) cDNA encoding a C2-domain in HEK-293 cells.PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells.
P2860
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P2860
PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
PTEN status switches cell fate ...... exposed to ionizing radiation
@ast
PTEN status switches cell fate ...... exposed to ionizing radiation
@en
type
label
PTEN status switches cell fate ...... exposed to ionizing radiation
@ast
PTEN status switches cell fate ...... exposed to ionizing radiation
@en
prefLabel
PTEN status switches cell fate ...... exposed to ionizing radiation
@ast
PTEN status switches cell fate ...... exposed to ionizing radiation
@en
P2093
P2860
P356
P1476
PTEN status switches cell fate ...... exposed to ionizing radiation
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2010.139
P577
2010-11-12T00:00:00Z