Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. - Wikidata - wikimedia - TriplyDB

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.

http://www.wikidata.org/entity/Q35095572

about

Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury An ocular view of the IGF-IGFBP system IGF-I in the clinics: Use in retinopathy of prematurity Muscle microvasculature's structural and functional specializations facilitate muscle metabolism.The mouse retina as an angiogenesis model.Current and future pharmacological intervention for diabetic retinopathy.Medical treatment of diabetic retinopathy with somatostatin analogues.Gene expression programs of mouse endothelial cells in kidney development and disease.Hyperinsulinemia Down-Regulates TLR4 Expression in the Mammalian Heart.Gal-geun-dang-gwi-tang improves diabetic vascular complication in apolipoprotein E KO mice fed a western diet.Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis An eye on insulin Insulin-like growth factor 1 (IGF-1) stabilizes nascent blood vessels The therapeutic potential of somatostatin receptor ligands in the treatment of obesity and diabetes.Transplantation of Human Neural Progenitor Cells Expressing IGF-1 Enhances Retinal Ganglion Cell Survival.Does Insulin Like Growth Factor-1 (IGF-1) Deficiency Have a "Protective" Role in the Development of Diabetic Retinopathy in Thalassamia Major Patients?IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis.Cell and molecular mechanisms of insulin-induced angiogenesis.Recombinant human insulin-like growth factor I (IGF-I): risks and benefits of normalizing blood IGF-I concentrations.Spare the rod and spoil the eye.Ageing and metabolism: drug discovery opportunities.IGF-1 and retinopathy of prematurity in the preterm infant.Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells.Liver sinusoidal endothelial cells link hyperinsulinemia to hepatic insulin resistance Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.Insulin-like growth factor I (IGF-I)-induced chronic gliosis and retinal stress lead to neurodegeneration in a mouse model of retinopathy Angiogenesis associated with visceral and subcutaneous adipose tissue in severe human obesity Short hairpin RNA-mediated knockdown of VEGFA in Müller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity.Inhibition of EGF signaling protects the diabetic retina from insulin-induced vascular leakage.Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors.Age-associated increase in cleaved caspase 3 despite phosphorylation of IGF-1 receptor in the rat retina.The role of liver-derived insulin-like growth factor-I.Phosphoinositide 3-kinase signaling in the vertebrate retina.Pro-angiogenic Role of Insulin: From Physiology to Pathology.The role of IGF-1 resistance in obesity and type 2 diabetes-mellitus-related insulin resistance and vascular disease.The IGF-1 receptor and regulation of nitric oxide bioavailability and insulin signalling in the endothelium.Neurodegeneration as a primary change and role of neuroprotection in diabetic retinopathy.Oxidative stress: A cause and therapeutic target of diabetic complications.Altered insulin signaling in retinal tissue in diabetic states.A histological and immunohistochemical study of the effects of N-acetyl cysteine on retinopathy of prematurity by modifying insulin-like growth factor-1.

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P2860

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.

http://www.wikidata.org/entity/Q35095572

description

2003 nî lūn-bûn

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2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2003 թվականի հունիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Knockout of insulin and IGF-1 ...... st retinal neovascularization.

@ast

Knockout of insulin and IGF-1 ...... st retinal neovascularization.

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type

label

Knockout of insulin and IGF-1 ...... st retinal neovascularization.

@ast

Knockout of insulin and IGF-1 ...... st retinal neovascularization.

@en

prefLabel

Knockout of insulin and IGF-1 ...... st retinal neovascularization.

@ast

Knockout of insulin and IGF-1 ...... st retinal neovascularization.

@en

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Journal of Clinical Investigation

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Knockout of insulin and IGF-1 ...... st retinal neovascularization.

@en

P2093

David Vicent

http://www.w3.org/2001/XMLSchema#string

George L King

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Kiyoshi Suzuma

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Martin Holzenberger

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Masashi Yanagisawa

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Tatsuya Kondo

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P2860

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

Role of endothelium-derived nitric oxide in the regulation of blood pressure

Reduced severity of oxygen-induced retinopathy in eNOS-deficient mice.

Lowering the risk of visual impairment and blindness.

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders.

Protein kinase C activation and the development of diabetic complications.

Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability.

Rapid tightening of blood glucose control leads to transient deterioration of retinopathy in insulin dependent diabetes mellitus: the Oslo study.

Endothelial response to hypoxia: physiologic adaptation and pathologic dysfunction.

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance.

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1835-1842

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12

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111

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12813019

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neovascularization

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161423

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