Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival
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Nuclear PI3K signaling in cell growth and tumorigenesisPIP kinases define PI4,5P₂signaling specificity by association with effectorsNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsPhosphoinositide 3-kinase p85beta regulates invadopodium formation.Comprehensive identification of mutational cancer driver genes across 12 tumor types.ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER.Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.Measurement of PIP3 levels reveals an unexpected role for p110β in early adaptive responses to p110α-specific inhibitors in luminal breast cancer.PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatus.Phosphatidylinositol-3,4,5-trisphosphate: tool of choice for class I PI 3-kinases.Discovery of a novel target for cancer: PRR14Classes of phosphoinositide 3-kinases at a glance.Nuclear phosphoinositides and their roles in cell biology and disease.Nuclear phosphoinositides and their impact on nuclear functions.PI-3 kinase p110β: a therapeutic target in advanced prostate cancers.CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells.Nuclear transport: a switch for the oxidative stress-signaling circuit?A polybasic motif in ErbB3-binding protein 1 (EBP1) has key functions in nucleolar localization and polyphosphoinositide interactionCell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity.Decatenation checkpoint-defective melanomas are dependent on PI3K for survival.Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms.Phosphoinositide 3-kinase beta controls replication factor C assembly and function.Phosphoinositide 3-kinase beta protects nuclear envelope integrity by controlling RCC1 localization and Ran activity.Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation.p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression.PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors.Dynamics of GFP-Fusion p110α and p110β Isoforms of PI3K Signaling Pathway in Normal and Cancer Cells.CXCL12-mediated murine neural progenitor cell movement requires PI3Kβ activation.New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response.
P2860
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P2860
Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Nuclear but not cytosolic phos ...... tial function in cell survival
@ast
Nuclear but not cytosolic phos ...... tial function in cell survival
@en
type
label
Nuclear but not cytosolic phos ...... tial function in cell survival
@ast
Nuclear but not cytosolic phos ...... tial function in cell survival
@en
prefLabel
Nuclear but not cytosolic phos ...... tial function in cell survival
@ast
Nuclear but not cytosolic phos ...... tial function in cell survival
@en
P2860
P50
P356
P1476
Nuclear but not cytosolic phos ...... tial function in cell survival
@en
P2093
Isabel Cortes
P2860
P304
P356
10.1128/MCB.01313-10
P407
P577
2011-03-07T00:00:00Z