about
Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher diseaseEffects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and StabilityFold designability, distribution, and diseaseLinking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death.Delivery of lysosomal enzymes for therapeutic use: glucocerebrosidase as an example.The endoplasmic reticulum as a potential therapeutic target in nonalcoholic fatty liver disease.Using peptides to study protein-protein interactions.Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view.Palmitoyl:protein thioesterase (PPT1) inhibitors can act as pharmacological chaperones in infantile Batten disease.Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin.Sodium 4-phenylbutyrate ameliorates the effects of cataract-causing mutant gammaD-crystallin in cultured cells.Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck.A systematic investigation of iminosugar click clusters as pharmacological chaperones for the treatment of Gaucher disease.New treatments for denervating diseases.Trehalose and 6-aminohexanoic acid stabilize and renature glucose-6-phosphate dehydrogenase inactivated by glycation and by guanidinium hydrochloride.4-Phenylbutyrate restores the functionality of a misfolded mutant low-density lipoprotein receptor.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Chemical chaperones--a new concept in drug research.
@ast
Chemical chaperones--a new concept in drug research.
@en
type
label
Chemical chaperones--a new concept in drug research.
@ast
Chemical chaperones--a new concept in drug research.
@en
prefLabel
Chemical chaperones--a new concept in drug research.
@ast
Chemical chaperones--a new concept in drug research.
@en
P2860
P356
P1433
P1476
Chemical chaperones--a new concept in drug research.
@en
P2093
Michaela Wendeler
Thomas Kolter
P2860
P304
P356
10.1002/CBIC.200390045
P577
2003-04-01T00:00:00Z