Keratinocytes from patients lacking collagen XVII display a migratory phenotype - Wikidata - wikimedia - TriplyDB

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

http://www.wikidata.org/entity/Q35098451

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Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes Tension in Cancer Shedding of collagen XVII ectodomain depends on plasma membrane microenvironment Keratins mediate localization of hemidesmosomes and repress cell motility Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration.Collagenous transmembrane proteins: recent insights into biology and pathology.The laminin family.Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.Molecular identification of collagen 17a1 as a major genetic modifier of laminin gamma 2 mutation-induced junctional epidermolysis bullosa in mice.Type XVII collagen regulates lamellipod stability, cell motility, and signaling to Rac1 by targeting bullous pemphigoid antigen 1e to alpha6beta4 integrin Dynamic interactions of epidermal collagen XVII with the extracellular matrix: laminin 332 as a major binding partner PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.Collagen XVII/BP180: a collagenous transmembrane protein and component of the dermoepidermal anchoring complex.The extracellular matrix in oral squamous cell carcinoma: friend or foe?A hemidesmosomal protein regulates actin dynamics and traction forces in motile keratinocytes.Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.Effects of constitutively active GTPases on fibroblast behavior.The human papillomavirus type 8 E2 protein suppresses beta4-integrin expression in primary human keratinocytes.Basement membranes and human disease.Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin Basement membranes in development and disease.Genetic analyses of integrin signaling.The extracellular matrix of the dermis: flexible structures with dynamic functions.Collagen XVII: a shared antigen in neurodermatological interactions?Molecular architecture and function of the hemidesmosome.Molecular architecture and function of the hemidesmosome.Type XVII collagen (BP180) can function as a cell-matrix adhesion molecule via binding to laminin 332.Significant Role of Collagen XVII And Integrin β4 in Migration and Invasion of The Less Aggressive Squamous Cell Carcinoma Cells.Coiled coils ensure the physiological ectodomain shedding of collagen XVII.Human bullous pemphigoid antigen 2 transgenic skin elicits specific IgG in wild-type mice.Focal Contact and Hemidesmosomal Proteins in Keratinocyte Migration and Wound Repair.Extracellular cleavage of collagen XVII is essential for correct cutaneous basement membrane formation.Mutations in collagen, type XVII, alpha 1 (COL17A1) cause epithelial recurrent erosion dystrophy (ERED).Targeting of Cell Surface Proteolysis of Collagen XVII Impedes Squamous Cell Carcinoma Progression.Amino acid duplication in the coiled-coil structure of collagen XVII alters its maturation and trimerization causing mild junctional epidermolysis bullosa.Homeostasis, regeneration and tumour formation in the mammalian epidermis

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P2860

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

http://www.wikidata.org/entity/Q35098451

description

2004 nî lūn-bûn

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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

@ast

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

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type

label

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

@ast

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

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prefLabel

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

@ast

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

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P1433

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S0002-9440(10)63762-5

P1433

The American Journal of Pathology

P1476

Keratinocytes from patients lacking collagen XVII display a migratory phenotype

@en

P2093

Gretel Chometon

http://www.w3.org/2001/XMLSchema#string

Kaisa Tasanen

http://www.w3.org/2001/XMLSchema#string

Lucy Tunggal

http://www.w3.org/2001/XMLSchema#string

Monique Aumailley

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P2860

Mutations in the 180-kD bullous pemphigoid antigen (BPAG2), a hemidesmosomal transmembrane collagen (COL17A1), in generalized atrophic benign epidermolysis bullosa

A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresia

Cloning of the human type XVII collagen gene (COL17A1), and detection of novel mutations in generalized atrophic benign epidermolysis bullosa

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly

The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome

Laminin 5 binds the NC-1 domain of type VII collagen

Three novel homozygous point mutations and a new polymorphism in the COL17A1 gene: relation to biological and clinical phenotypes of junctional epidermolysis bullosa

The short arm of the laminin gamma2 chain plays a pivotal role in the incorporation of laminin 5 into the extracellular matrix and in cell adhesion

Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180

Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin

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2027-2038

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scholarly article

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10.1016/S0002-9440(10)63762-5

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6

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Leena Bruckner-Tuderman

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2004-06-01T00:00:00Z

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15161638

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1615787

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